Feelings of tightness in the chest, anxiety, sleepless nights, heart pain and heavy breathing are the main prescriptions for which Corvalol helps. Most people consider this drug almost a panacea for all ills and always keep a bottle or two of strong-smelling drops in their medicine cabinet. However, few people think about what this remedy is, what is in its composition, what its therapeutic effect is based on, and, most importantly, how to use it correctly.

Corvalol - composition

In pharmacology, the drug Corvalol is produced in both tablet and liquid form. However, for home use, alcohol-containing drops are more common, due to their fast action. But it’s more convenient to take the tablets with you. The basic composition of the two types of the drug is the same:

1. Ethyl bromizovalerianate has a strong sedative, antispasmodic and soporific effect.
2. Luminal (phenobarbital) has a depressant effect on the central nervous system, thereby causing drowsiness, calming and reducing reaction. The concentration of the drops affects the effect from a weak sedative to a strong hypnotic.
3. Peppermint essential oil in Corvalol has a wide spectrum of action:

• dilates blood vessels;
• carminative;
• spasmolytic;
• antiseptic.

Corvalol tablets - composition

Corvalol tablets are available in packs of 10, 30 or 50 pieces in cellular blisters. The active ingredients contained in the drug per tablet have the following proportions:

• mint essential oil– 580 mcg;
• Luminal – 7.5 mg;
• ethyl bromizovaleriant – 8.2 mg.

In addition, a number of auxiliary ingredients include Corvalol. The composition of the tablet is also supplemented by substances that ensure the proper pharmacological action of the drug, taking into account its pharmacokinetics:

• magnesium stearate – 1 mg;
• beta-cyclodextrin – 55.5 mg;
• magnesium aluminum metasilicate – 4 mg;
• potato starch– 37.5 mg;
• milk sugar – 83 mg;
• talc – 2 mg.

Corvalol - composition in drops

Corvalol drops are a colorless liquid with characteristic odor, more often than tablets, they are used in home treatment. The medicine is produced in vials with droppers of 25 or 50 ml. They are based on:

• water – 100 ml;
• oils – 0.14 g;
• ethyl alcohol – 58 ml;
• caustic soda – 0.31 g;
• phenobarbital – 1.8 g;
• ethyl bromoisovalerate – 2 g.

Why take Corvalol?

To the question “what does Corvalol help with?” Most people taking this drug will answer that they take it for heart pain. However, it is difficult to call Corvalol Forte a medicine that can cure even a heart disease or any other disease. This remedy is aimed at eliminating certain symptoms of nervous system disorders. Yes, Corvalol is able to relieve heart pain, but only that associated with anxiety, worries, and stress. However, he cannot stop the heart attack pain.

The main symptoms that Corvalol helps with are:

• anxiety;
• nervousness;
• panic;
• consequences of nervous disorders.

Corvalol for VSD

- This is a vivid example of the fact that all diseases begin with nerves. The main treatment for VSD is aimed at relieving symptoms, which is what Corvalol helps with in the best possible way. This drug fights nervous disorders, which, in essence, is what VSD is:

1. Peppermint essential oil dilates the blood vessels of the heart.
2. Bromine fights anxiety and stress.
3. Phenobarbital is a powerful tranquilizer. It has strong hypnotic and sedative qualities.
4. Corvalol has worked well for tachycardia.

Corvalol for blood pressure

Due to the properties of the components of Corvalol to have an inhibitory effect on the vasomotor center and an antispasmodic effect on the heart vessels, an unexpressed hypotensive effect of the drug on the body is achieved. However, the fact remains that Corvalol high blood pressure If it helps, it is very weak. So you should not rely on this remedy for arterial hypertension, which requires completely different treatment. Yes, Corvalol is able to reduce blood pressure, but it cannot stop it, nor can it maintain normal blood pressure.

Corvalol for insomnia

Is it possible to take Corvalol for insomnia? Sleep disturbance is a direct indication of taking this drug in any form, be it drops or tablets. However, it is worth keeping in mind that the dose of the drug, just like the course of treatment, is selected individually in each specific case. According to the instructions, you should drink Corvalol as follows:

1. If you drink the solution, then 20-25 drops dissolved in 50 ml of water will be a sufficient dose. However, you should not take the medicine more than three times a day. In case of severe stress and tachycardia, the dose of the drug can be increased to 40 drops per dose, but no more.
2. If you take Corvalol in tablet form, then one tablet three times a day before each meal is enough. For severe stress and tachycardia, you can increase the dose to 3 tablets.
3. Children over 6 years old should not exceed the daily dose of 12 drops.
4. The course of taking Corvalol can vary from 1 week to 2 months, according to the doctor’s instructions.

Corvalol for heart pain

The use of Corvalol drops is very often associated with cardiac pathologies. However, in the presence of structural cardiac disorders, associated, for example, with atherosclerosis, dripping these drops over and over again in the hope of healing is not only pointless, but also fraught. Yes, Corvalol can and will help with arrhythmia, calming the nerves and thereby relieving the symptom, but the disease will remain and worsen over time, even to the point of fatal consequences.

Corvalol is a symptomatic remedy and can relieve the negative manifestations of stress and neuroses, so doctors often recommend taking it for:

1. Functional cardiac disorders:
   • tachycardia;
   • pain from overexertion and anxiety.
2. Overexcitation with vegetative symptoms:
   • cardiopalmus;
   • sweating;

How to take Corvalol?

Depending on the reason for which Corvalol is prescribed, the dosage of the drug may be prescribed differently by the attending physician. In this case, the doctor must take into account the general condition of the patient, be sure that there are no contraindications or violations on the part of the patient. of cardio-vascular system. If, while taking Corvalol, the patient’s condition worsens: chest pain appears, anxiety increases, or abdominal discomfort is observed, then the medication should be stopped and immediately contact your local physician.

How to take Corvalol tablets?

A more convenient form of medication to take is tablets. How to take Corvalol tablets? This drug is prescribed 1, less often 2 tablets three times a day. They should be taken before meals with plenty of water. In case of severe symptoms, for example, with tachycardia, it is possible to increase the single dose of the drug to three tablets per dose.

How to take Corvalol drops?

An alcohol solution in a bottle with a dropper is the most common form of the drug Corvalol. The use of this product is dosed in drops. At the same time, they can be applied either to a piece of sugar or dissolved in a small amount of water. This one is released sedative without a prescription, so people mostly drink Corvalol, dosing the drops themselves according to the instructions:

1. Dissolve 15-30 drops of the drug in a glass of water and take three times a day.
2. For tachycardia, a single dose can be increased to 40 drops.
3. The daily dose for children is 3-12 drops, depending on the clinical picture of the disease and the age of the child.

Corvalol - side effects

Regardless of the fact that you can easily count a dozen or two symptoms that Corvalol helps with, this drug still has many negative aspects and consequences that quickly disappear when the drug is discontinued or its dose is reduced:

• drowsiness;
• decreased concentration;
• allergy;
• dizziness;
• digestive system disorders;
• slow heart rate;

Long-term use of Corvalol can also lead to unpleasant consequences:

• addiction;
• withdrawal syndrome;
• addiction.

When bromine accumulates in the body, the following symptoms may occur:

• depression;
• rhinitis;
• diathesis;
• ataxia;
• conjunctivitis;
• impotence;
• respiratory diseases;
• kidney and liver poisoning.

• depression of the central nervous system;
• ataxia;
• hypotension;
• overexcitement;
• vertigo;
• general weakness;
• bromism;
• nystagmus.

In case of an overdose of Corvalol, emergency gastric lavage and symptomatic therapy are performed. When the central nervous system is depressed, stimulant drugs are prescribed:

• Caffeine;
• Niketamide;
• Cordiamine.

Corvalol - contraindications

Corvalol contains Luminal, as a result, patients taking this drug are advised to refrain from potentially hazardous activities that require high level attention and concentration, quick reaction. For example, when driving vehicles or other complex mechanisms, or when working at height.

Is Corvalol safe for pregnant women? The absence of alcohol in the component composition of the tablets allows it to be taken by some groups of patients. However, pregnant women are not included in this list due to the presence in the drug, whether tablet or in the form alcohol solution, phenobarbital. In general, Corvalol has many contraindications, which are largely associated with phenobarbital, ethanol and bromine, which can accumulate in the body:

• individual intolerance to the ingredients of the drug;
• severe liver and kidney dysfunction;
• perinatal period and lactation period;
• epileptic syndrome and seizures;
• alcohol addiction;
• consequences of traumatic brain injury.

Persons under 18 years of age should take the drug with caution.

Corvalol - analogues

Corvalol drops and tablets have numerous analogues. Despite the different compositions and component inconsistencies with each other, the sedative effect of all these drugs is pronounced:

1. is a synonym for Corvalol. This drug was invented in Germany in pre-war times and is still produced by only one company.
2. Novo-passit has a completely natural composition - herbs infused with alcohol, which together show a powerful sedative effect.
3. Barboval.
4. Adonis-bromine.

Neurotic conditions, insomnia and other disorders require immediate consultation with a doctor. As a rule, for such diseases, patients are prescribed vasodilators and To the most popular and inexpensive drugs include the well-known medicine “Corvalol”. Instructions for use and reviews of the drug will be discussed below.

Form, description of the medicine, composition and packaging

In what form is the drug Corvalol produced? Consumer reviews report that this product can be purchased in two forms:

• Drops are transparent with a characteristic odor for oral administration. They contain ethyl ester of alpha-bromisiovaleric acid, phenobarbital and pepper. This product is produced in dark glass bottles.
• "Corvalol" tablets. Reviews say that the active ingredients of this form are peppermint oil, ethyl ester of α-bromoisovaleric acid and phenobarbital. Beta-cyclodextrin, potato starch, lactose monohydrate, microcrystalline cellulose and magnesium stearate are used as additional substances. The tablets have a round and flat shape, beveled edges, and are white with inclusions. They go on sale in cell packaging.

Pharmacological characteristics

What is the drug "Corvalol"? Reviews from experts indicate that this is a combined remedy, the effect of which is determined by the properties of the ingredients included in its composition.

This medicine has an antispasmodic and sedative effect. In addition, it facilitates the onset of sleep.

Properties of the drug

What properties are inherent in Corvalol drops and tablets? Reviews from doctors claim that the effectiveness of this remedy has been confirmed by many years of experience.

Ethyl bromoisovalerianate, or the so-called ethyl ester of alpha-bromoisovaleric acid, has a sedative (similar to valerian) and antispasmodic effect, which is caused by irritation of receptors in the nasopharynx and oral cavity, as well as a decrease in reflex excitability in the central nervous system and increased inhibition in neurons of the subcortical structures and cerebral cortex . In addition, the medication in question reduces the activity of the central vasomotor centers and has a local antispasmodic effect (mainly on smooth muscles).

A component of the drug, phenobarbital, enhances the sedative effect of other substances, facilitates the onset of sleep and reduces excitation of the central nervous system.

As for peppermint oil, it has antispasmodic, vasodilating (reflex), antiseptic and choleretic effects. It is capable of irritating cold receptors in the oral mucosa and reflexively dilating the blood vessels of the brain and heart. Besides, this component eliminates signs of flatulence (due to irritation of receptors in the gastrointestinal mucosa) and enhances intestinal motility.

Indications

What is the medication Corvalol prescribed for? Reviews report that this remedy is used as a vasodilator and sedative for diseases such as:

It should also be said that Corvalol is used as an antispasmodic for spasms of the muscles of the gastrointestinal tract (for example, with biliary or intestinal colic).

Contraindications

Like any medicine, Corvalol also has contraindications. These include:

• hypersensitivity to drug substances;
• severe impairment of the kidneys and liver;
• breastfeeding (if it is necessary to use medication during breastfeeding, it is necessary to decide on cessation of lactation);
• lactase deficiency;
• pregnancy period;
• minor age (safety and effectiveness have not been established);
• lactose intolerance;
• glucose-galactose malabsorption (since the drug contains lactose).

The drug "Corvalol": instructions for use (tablets)

Reviews from experts report that you can take this medication without a doctor’s prescription. The dosage of the medicine is selected individually.

The medication is taken orally before meals with water. For adults, the drug is prescribed 1-2 tablets twice a day. For tachycardia, the single dosage can be increased to three tablets per day. The maximum permissible dose is 6 tablets.

The duration of medication is determined individually, depending on the patient’s condition.

How are Corvalol drops (tincture) taken?

Reviews say that the drug in the form of drops must be taken orally before meals. The medication is prescribed in an amount of 15-30 drops. They are dissolved in a small volume of drinking water (about 30-50 ml) twice or thrice a day.

If necessary, a single dosage of the medicine (for example, for tachycardia) can be increased to 40-50 drops.

As for children, depending on clinical picture diseases and age, they are prescribed 3-15 drops per day.

The duration of medication use in children is determined individually.

Does herpes and acne cure?

Does Corvalol help with herpes? Feedback from supporters traditional medicine They say that when the first signs of this disease appear (for example, discomfort, twitching of the lips and itching), a cotton swab is soaked in the medicine and then pressed against the sore spot for a few seconds. If this procedure is carried out in a timely manner, herpetic rashes do not appear.

It should also be noted that the medicine in question also treats blisters that have already appeared. They are lubricated with the drug until the wounds disappear.

Does Corvalol help with acne? Consumer reviews say that this medication also effectively treats acne. They are treated in exactly the same way as herpes.

Side effects

Corvalol tablets and drops often cause drowsiness, decreased concentration, slow heart rate, dizziness and allergic reactions. Also, while taking this drug, patients may experience disorders of the digestive tract.

Usually all of the above side effects go away on their own when the dosage of the medication is reduced or its use is stopped.

With prolonged use of the medication, drug dependence, addiction, withdrawal syndrome, as well as bromism and the accumulation of bromine in the body may develop.

There is no experience using this product in children under 18 years of age. Therefore, minors are prohibited from taking it.

You should not drink alcohol while using the drug. It is also required to refrain from engaging in hazardous activities that require a person to react quickly and have increased concentration (including when working with complex mechanisms and driving vehicles).

Similar remedies and cost of medicine

The price of the drug "Corvalol" is the lowest among drugs with a similar effect. You can buy a bottle of drops or tablets for 15-20 rubles. It is the low cost of the drug that contributes to its particular popularity among patients.

What can replace this remedy if there are contraindications? According to information from experts, this drug has many analogues. The closest properties include the following: “Cardiolin”, “Pumpan”, “Aspirin Cardio”, “Neocardil”, “Captopres”, “Nicotinic acid”, “Inosine”, “Sotalex” and others. It should immediately be noted that the effectiveness of these drugs and their method of administration may differ significantly from the same indicators of the drug Corvalol. Therefore, only an experienced specialist should replace the mentioned medication with the listed medications. Moreover, most of them are prohibited from being given to young children.

Medical and consumer reviews

What do patients say about the drug Corvalol? Reviews from most consumers are positive. They claim that this medication quickly eliminates irritability, restores heart function and helps normalize sleep. Moreover, many patients choose this remedy because it not only effectively copes with the assigned tasks, but also has a very low cost.

However, it should be noted that, in addition to positive feedback, the medication in question also has negative responses. According to doctors, Corvalol drops and tablets are ineffective compared to their analogues. This medicine has a sedative and antispasmodic effect only for a short period of time. After stopping the medication bad feeling often returns.

Consumers did not report any side effects while taking this drug.

In our turbulent times, every second person suffers from nervous system disorders: irritability, anxiety, insomnia, stress. It is for this reason that sedatives, sleeping pills and antidepressants are so popular. On the modern pharmacological market you can find dozens medicines, which normalize the functioning of the nervous system, but many patients still prefer the long-known Corvalol.

The drug is based on menthol, ethylbromoisovalerate and phenobarbital and has a calming, antispasmodic effect. It is extremely popular due to its ease of use, low cost and effectiveness. However, this drug is potentially dangerous if taken incorrectly, as it contains artificial psychotropic substances and a high concentration of ethanol.

Corvalol - description of the pharmaceutical form

Corvalol is combination drug based on plant and artificial components. It is a structural analogue of Valocordin, which was released for sale in Germany before the war. In modern times, the drug is quite popular in Russia and other countries of the former USSR, as well as Asia. In Europe and the USA it was banned long ago because of the phenobarbital it contains.

The main components of Corvalol are ethyl bromizovalerianate, phenobarbital and menthol oil.

Corvalol is produced in two pharmaceutical forms - tablets and drops. Drops are considered the most popular due to their ease of use and rapid therapeutic effect.

Corvalol drops contain the following substances:

• α-bromoisovaleric acid ethyl ester (ethyl bromoisovalerianate);
• phenobarbital;
• menthol oil;
• ethanol (96%);
• distilled water;
• sodium isovalerate.

The solution contains about 50% ethanol. In appearance, it is a colorless liquid with a menthol aroma.

The composition of Corvalol drops may vary slightly. For example, Corvalol N tincture, in addition to the active substances described above, contains hop oil. As additional components: sodium acetate trihydrate, acetic acid solution, water, ethanol (96%).

The drug provides a sedative, vasodilator and antispasmodic effect.

Component Properties

Corvalol eliminates spasm of smooth muscles, has a sedative effect and can help with mild sleep disorders. The therapeutic effect of the drug is determined by its components.

Ethylbromoisovalerate and alcohol affect the receptors of the inner lining of the mouth and pharynx, reduce the excitability of the central nervous system, provoke an inhibitory effect on the cerebral cortex and subcortical nerve centers. Thanks to these substances, the drug has an antispasmodic and sedative effect similar to Valerian tincture. In large dosages, the sedative exhibits a pronounced hypnotic effect.

Phenobarbital has a sedative effect; this substance inhibits the transmission of nerve impulses to the cortex and subcortex of the brain. This component helps relieve irritation, under its influence the patient feels drowsiness, and the reaction rate decreases. The degree of suppression of excitatory impulses depends on the portion of drops: the recommended dose will have a calming effect, and in case of an overdose, a pronounced hypnotic effect will appear.

Corvalol has a sedative, antispasmodic, vasodilator effect

The components of Corvalol inhibit the activity of the vasomotor (vasomotor) center. Phenobarbital relaxes vascular smooth muscle, resulting in a moderate hypotensive effect of the drug. However, when blood pressure increases, it is recommended to take other medications; Corvalol is not suitable for this purpose. The drops slightly reduce blood pressure, but they are not able to eliminate the excessive increase in blood pressure during a hypertensive crisis.

Menthol oil is an antispasmodic, promotes vasodilation, enhances intestinal motility, eliminating excess gas formation. Thanks to peppermint oil, the drops have a pleasant refreshing taste and a disinfecting effect.

The tincture is taken before meals, first dissolved in a small dose of filtered water or by dropping the required portion onto refined sugar.

Many patients are interested in the question of how long it takes for Corvalol to work. The therapeutic effect appears 20 minutes after administration and lasts for 3–6 hours. Most of the medicine begins to be absorbed through the oral mucosa.

In patients who have previously taken medications containing barbituric acid before therapeutic effect decreases due to rapid metabolism of phenobarbital in the liver.

Purpose of Corvalol

Patients are interested in the question of what the drug helps with. Corvalol drops are not a medicine, it is a symptomatic drug that is used to relieve certain signs of mental disorders. That is, the remedy is not able to cure heart disease, renal colic, and insomnia. Some will disagree, because after taking the drops they really disappear painful sensations in heart. However, the medicine can relieve pain as a result of stress or a nervous breakdown. But if we are talking about pain due to angina or heart attack, then Corvalol will not help.

Corvalol is prescribed to eliminate symptoms of neurotic disorders

The tincture is taken to calm the nerves and fall asleep easier, but they will not help if you have developed stress or anxiety disorder. Every patient knows this long time takes drops.

Some patients take the drug for so long that they become dependent on it and use it on every occasion. However, Corvalol is recommended to be taken as prescribed by a doctor, since many symptoms (pain in the left side of the chest, kidneys, insomnia) require clarification of the cause and adequate treatment.

Indications for use of Corvalol:

• Neurotic disorders.
• Vegetative-vascular dystonia, arterial hypertension (complex treatment).
• Insomnia.
• Tachycardia, spasm of the coronary arteries (if the symptoms are mild).
• Intestinal spasm due to neurovegetative disorders.

Thus, Corvalol drops are able to eliminate pain due to nervous experiences, and not against the background of structural changes in the coronary vessels or heart muscle.

Precautionary measures

As indicated in the instructions for use of Corvalol in drops, the drug is prohibited in the following cases:

• Intolerance to the ingredients of the drug.
• Allergy to bromine.
• Chronic heart failure (severe).
• Hepatic porphyria.

Corvalol is contraindicated in case of allergies not to its components

In addition, drugs containing phenobarbital are prohibited from being taken by patients with heart attack (acute form), low blood pressure, stress, diabetes mellitus. The use of Corvalol is contraindicated in patients with drug addiction, medications, alcoholic drinks. This restriction applies to patients with impaired air flow through the bronchi due to narrowing or blocking of the air ducts, as well as for diseases of the respiratory organs with shortness of breath.

Patients with epileptic seizures take a sedative under the supervision of a doctor, serious illnesses liver. The tincture is allowed to be given to children only for medical reasons, and it is important to constantly monitor their condition.

Negative effects of tincture on humans:

• epigastric discomfort, difficulty defecating, nausea, vomiting, impaired liver function;
• neuromuscular disorders, involuntary eye movements of high frequency, slow reaction speed, dizziness, hallucinations, etc.;
• allergic reactions (including angioedema);
• disturbance of blood composition (decrease in the concentration of granulocytes, platelets, anemia);
• difficulty breathing;
• hypertonic disease, bradycardia.

Long-term use of Corvalol is harmful to health, in which case the likelihood of osteogenesis imperfecta (impaired bone formation) and the manifestation of symptoms of bromism increases ( chronic poisoning bromine): inhibition of the nervous system, stress, ataxia, disorientation, etc. If such signs appear, you should stop taking the drops and consult a doctor.

Dosage of Corvalol

Many patients are interested in the question of how to take Corvalol. As indicated in the instructions, the medicine should be taken by first mixing it with 50 ml of filtered water or dropping it on a piece of sugar. The correct time to take drops is 30–60 minutes before meals.

Drops are diluted with water and taken before meals

The dosage of the medicine depends on the symptoms, as well as the age of the patient. The usual dose of Corvalol is from 15 to 30 drops. For slight spasm of the heart vessels or tachycardia, take 40 to 50 drops. To make it easier to fall asleep, drink 30 drops of the tincture, after mixing it with water, half an hour before bed.

The second pressing question: “How often can you take Corvalol?” The frequency of taking the medicine depends on the clinical picture and age of the patient. Sometimes the drug is used once, and in other cases the recommended dose is 3 times a day.

Drug danger

Many people know about the beneficial properties of the sedative, but not everyone realizes how harmful Corvalol is if the rules for its use are violated. For example, ethyl ester of α-bromoisovaleric acid is a substance that has an antispasmodic effect. Depending on the portion of drops, the drug exhibits a sedative or hypnotic effect. This dosage is determined for each patient individually.

If the rules of administration are violated, the drug causes dangerous complications

Phenobarbital, which enters the body after consuming the usual dose of the drug (15 to 20 drops), causes a vasodilator and moderate sedative effect. The hypnotic effect does not appear after taking such a portion of drops.

Menthol oil also dilates blood vessels and relaxes smooth muscles. But when using a dose of 25 mg drops or more, intestinal motility decreases and constipation occurs.

In many European countries and the USA, the active ingredients of Corvalol are prohibited. For example, phenobarbital is dangerous for people, as it is considered a narcotic substance that provokes addiction. When Corvalol is taken systematically, this component provokes a decrease in cognitive functions: speech disorders, loss of short-term memory, unsteadiness when walking. In addition, there is an increased likelihood neurological disorders, withdrawal syndrome, sexual disorders.

With prolonged use of drops, the risk of bromine accumulation in the body and the development of intoxication increases.

Degrees of poisoning:

• Mild – general weakness, desire to sleep, muscle weakness, absent-mindedness, speech impairment, apathy, purpura (accumulation of blood under the skin, mucous membranes), etc.
• Average – pathologically prolonged sleep, involuntary secretion of saliva, increased, decreased muscle strength up to paralysis, hypotension, decreased amount of urine, dilated pupils.
• Severe - coma due to barbiturate intoxication, which is accompanied by respiratory failure, decreased reflexes, and loss of consciousness. In addition, it decreases arterial pressure, pathological noises occur during breathing, tachycardia, the skin and mucous membranes acquire a blue tint.

Functional heart failure continues to develop, after which the lungs often swell.

The lethal dose of drops is from 0.1 to 0.3 g/kg; the patient dies after taking 100 mg/kg of phenobarbital.

In case of mild intoxication, the stomach is washed and the victim is given enterosorbent drugs. In case of severe poisoning, cardiac massage and artificial respiration cannot be avoided. It is imperative to call ambulance.

Complications of intoxication, even with timely assistance, are quite dangerous - severe forms of dermatitis, functional failure of the heart, respiratory organs or kidneys in acute form. Therefore, the dosage of drops must be correct.

Effect of the drug on blood pressure

The effect of active substances on blood pressure can also be quite dangerous. This applies to patients who have hypotension, because Corvalol provokes a decrease in blood pressure (BP). It is for this reason that it is sometimes used for hypertension. However, it is recommended to use specially designed medications for this purpose.

Corvalol lowers blood pressure

Doctors allow taking drops in emergency cases, when blood pressure rises sharply and there are no means at hand to lower it. The recommended dose is 45 drops per 100 ml of hot boiled water. The medicine must be taken quickly. Therapeutic effect appears after half an hour. Thus, Corvalol will help not only calm the nerves, but also save a person from a hypertensive crisis.

Compatibility of Corvalol with alcohol

Many people know that Corvalol drops and alcoholic drinks are a dangerous mixture. After all, ethyl alcohol enhances the effect of the sedative drug. For this reason, the tincture is contraindicated in patients with alcohol addiction.

Corvalol should not be combined with alcoholic beverages.

When taken together, hepatocytes (liver cells) are damaged and a disulfram-alcohol reaction develops.

After ethanol penetrates into the bloodstream, the heartbeat quickens, blood pressure rises, and the nervous system is excited. But the drops act the opposite, that is, they reduce blood pressure and calm the heart. As a result, an imbalance occurs and the body is overloaded.

Menthol oil dilates blood vessels and thins the blood. In this case, alcoholic drinks enhance the effect of the component, which threatens internal hemorrhages.

Most dangerous consequence combinations of Corvalol with alcohol lead to cardiac arrest.

If a person often mixes the drug with alcoholic drinks, the likelihood of persistent drug dependence increases. This is explained by the presence of phenobarbital in the tincture.

It is strictly forbidden to drink Corvalol during a hangover, since after such a “cocktail” liver enzymes are released faster and metabolic processes are accelerated. As a result, ethanol is absorbed into the bloodstream faster and exhibits its negative effect.

Corvalol for pregnant and lactating women

According to the instructions, expectant mothers are prohibited from taking Corvalol. This is explained by the presence of phenobarbital, ethanol and other aggressive substances in the medication. In the first trimester of pregnancy, the drug can cause pathologies in the development of the fetus. And after taking the drug before childbirth, the likelihood of respiratory failure in infants increases.

Drops are not recommended for use during pregnancy and lactation

Menthol oil increases the tone of the uterine muscles. That is why drinking Corvalol during pregnancy is prohibited, otherwise there is a risk of placental abruption and fetal death.

Thus, the components of the tincture are extremely harmful to the fetus, and therefore taking it during pregnancy is strongly not recommended. In case of emergency, you can take the minimum dose, but only after your doctor's approval.

The use of Corvalol during lactation is also prohibited, since the active substances are quickly absorbed into the blood and enter the baby’s body along with milk.

Similar means

There are a lot of drugs with a similar effect that can replace Corvalol:

• Valerian
• Doppelhertz Melissa
• Corvaldin
• Novo-Passit
• Persen
• Bromized
• Nott, etc.

The closest in composition and principle of action are Corvalol and Valocordin

The most important analogue of Corvalol is Valocordin. The only difference between them is that Valocordin contains hop oil, which is absent in Corvalol drops. Otherwise, they are absolutely similar, this also applies to their actions.

Based on the foregoing, Corvalol drops are a fairly popular drug with a sedative, vasodilator, local anesthetic, antispasmodic, and also mild hypnotic effect. The symptomatic remedy is used to eliminate signs of neuroses. The medication contains quite dangerous components that cause addiction and negatively affect various organs (if the rules of administration are violated). To avoid adverse reactions Drops are recommended to be used only for medical reasons, and the dosage should be strictly adhered to.

Corvalol has long been not just a medicine, but an element of a subculture for older people, which is as integral an attribute of their lives as a cup of tea with their favorite TV series.

Its moderate sedative effect allows the drug to be used as a sedative for sleep disorders, increased irritability and neuroses, and the vasodilating effect helps to correct functional abnormalities of the cardiovascular system

On this page you will find all the information about Corvalol: full instructions on application to this medicine, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Corvalol. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug with sedative and antispasmodic effects.

Conditions for dispensing from pharmacies

Dispensed without a doctor's prescription.

Prices

How much does Corvalol cost? The average price in pharmacies is 30 rubles for drops and 130 rubles for tablets.

Release form and composition

The following dosage forms of Corvalol are produced:

• Drops (in dark glass dropper bottles of 10, 15, 25, 30 or 50 ml, 100 ml jars; 1 bottle or jar in a cardboard pack);
• Tablets - flat, round, beveled to the edge, white or almost white, with inclusions (in contour strip packs of 10 pcs.; in a cardboard pack of 2, 10, 30, 50 or 100 packs).

Composition of 1 tablet:

• Active ingredients: peppermint oil – 0.58 mg, ethyl ester of α-bromoisovaleric acid – 8.2 mg, phenobarbital – 7.5 mg;
• Auxiliary components: microcrystalline cellulose - 10.5 mg, magnesium stearate - 0.9 mg, beta-cyclodextrin - 55.55 mg, lactose monohydrate - 43.77 mg, potato starch - 13 mg.

Composition of 1 ml drops:

• Active ingredients: phenobarbital – 18.26 mg, ethyl ester of α-bromoisovaleric acid – 20 mg;
• Auxiliary components: peppermint oil, ethanol 95%, purified water, sodium hydroxide.

Pharmacological effect

Corvalol is a sedative and antispasmodic drug, the effect of which is determined by the components it contains.

1. Phenobarbital. The active phenobarbital is a sedative component that inhibits the spread of nerve impulses to neurons of the cerebral cortex. Thanks to this substance, a feeling of lethargy appears with a pronounced decrease in the speed of reactions. The compound calms the nervous system, inducing sleep. Useful for hyperactive individuals.
2. Peppermint oil. This substance is rich in menthol esters. When taking it, a person experiences vasodilation and increased intestinal contractility. Peppermint oil is an excellent antispasmodic for many internal structures. Corvalol has a mint flavor, which helps create oral cavity antiseptic effect.
3. Ethyl ester of a-bromoisovaleric acid. The alcohol contained affects the sensitive endings located in the pharynx and oral cavity, reducing the level of excitability of the nervous system. This creates a characteristic inhibition with the development of a sedative and antispasmodic effect. Taking large doses of the drug leads to the formation of a hypnotic effect.

Corvalol reduces the stimulating effect on the vasomotor centers, peripheral and coronary vessels, lowering total blood pressure, thereby relieving and preventing vascular spasm, especially the heart.

Indications for use

As a sedative and vasodilator, Corvalol is prescribed for the following diseases:

• vegetative lability;
• with insomnia, especially with difficulty falling asleep;
• neurotic conditions, irritability, hypochondriacal syndrome;
• disorders of the cardiovascular system (sinus, cardialgia, various blood pressure disorders).
• Corvalol is indicated as an antispasmodic for muscle spasms of organs gastrointestinal tract, such as intestinal or biliary colic.

What is the danger of Corvalol?

1. This is a popular remedy in the countries of the former USSR, but prohibited in Poland, Germany, the USA, Norway, and Lithuania. Prohibitive measures were taken due to the presence in Corvalol of the psychoactive compound phenobarbital, as well as a toxic bromine-containing component.
2. It is phenobarbital that causes rapid and strong addiction - in some cases, 2-3 weeks of taking the drug is enough to develop drug dependence. Moreover, phenobarbital causes not only physical, but also psychological dependence.
3. After stopping Corvalol, people develop the so-called “withdrawal” syndrome - a depressed state, the patient complains of constant nausea and intense headaches.

However, the medicine has one important advantage - it has the fastest and most powerful effect. If taken in small doses and extremely moderately, Corvalol can quickly, almost instantly, relieve anxiety. In general, the recommended doses of the drug are not dangerous, but the problem is that if you take it constantly, you will need to increase the dosage. The most dangerous thing is that these doses do not just increase each time, but lead to real pleasure: a depressed state and dizziness are replaced by euphoria immediately after taking the required dose.

Contraindications

For both dosage forms:

1. Lactation period (or breastfeeding should be stopped);
2. Severe liver/renal failure;
3. Hypersensitivity to components.

Tablets are also contraindicated in the following cases:

1. Pregnancy;
2. Lactose intolerance, lactase deficiency, glucose-galactose malabsorption (due to lactose content);
3. Age up to 18 years (experience of using the drug in this dosage form absent in this age group).

With extreme caution, Corvalol in the form of drops can be prescribed during pregnancy.

Use during pregnancy and lactation

Corvalol is contraindicated during pregnancy, since phenobarbital can have a very adverse effect on the development of the baby.

Phenobarbital has a depressant effect on the nervous system of both mother and child, impairs blood clotting, causing bleeding in the first days of life in a newborn. Abuse of Corvalol in the third trimester of gestation causes addiction and subsequent withdrawal syndrome, which can be observed in the child in the development of seizures and severe excitability after childbirth or in the first two weeks of life.

The use of the drug during breastfeeding is also contraindicated.

Instructions for use

The instructions for use indicate that Corvalol drops are taken orally before meals.

• How much does an adult need? Usually this is 15-30 drops, they must first be dissolved in a small amount (30-50 ml) of water, 2-3 times a day. A single dose, if necessary (for example, for tachycardia) can be increased to 40-50 drops.
• Children – 3-15 drops/day (depending on age and clinical picture of the disease).

Instructions for tablets

The dose is set individually. Take orally, before meals, with water. Adults are usually prescribed 1-2 tablets 2 times a day. For tachycardia, the single dose can be increased to 3 tablets. The maximum daily dose is 6 tablets.

The duration of use of the drug is determined by the doctor individually.

Side effects

If the dosages specified in the instructions are followed, Corvalol drops are well tolerated by patients. In some cases, persons with increased individual sensitivity may develop the following adverse reactions:

1. Tremor of the limbs;
2. Nausea, vomiting, bloating;
3. Dizziness, weakness, drowsiness, lethargy, lethargy;
4. Slowing heart rate per minute, lowering blood pressure.

As a rule, all these phenomena quickly resolve on their own after discontinuation of therapy.

Overdose

Overdose is possible in case of frequent and long-term use of the drug, which is associated with the process of cumulation of its components. Quite a long and constant use can provoke dependence, psychomotor agitation and withdrawal symptoms. Abrupt refusal to take Corvalol can provoke withdrawal syndrome.

Symptoms of overdose include:

• depression of the central nervous system;
• confusion;
• dizziness;
• drowsiness;
• ataxia;
• falling asleep.

In particularly severe cases of drug poisoning, respiratory failure, tachycardia, arrhythmia, low blood pressure, collapse and coma are possible.

An overdose of Corvalol is treated with symptomatic therapy. Niketamide and caffeine are indicated for depression of the nervous system.

special instructions

There is no experience with the use of the drug in children under 18 years of age.

You should not drink alcohol while using the drug.

Drug interactions

Medicines that depress the central nervous system enhance the effect of the drug.

The effect of the drug is enhanced by the use of valproic acid drugs.

Phenobarbital (an inducer of microsomal oxidation) may reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin, glucocorticosteroids, oral contraceptives); enhances the effect of local anesthetics, analgesics and hypnotics. The drug increases the toxicity of methotrexate.

Perhaps there is no other sedative and heart remedy that would be as popular as the well-known Corvalol. Even in the 21st century, many people, especially the older generation, consider it the best remedy from heart pain, insomnia and anxiety. Almost 100 years of active use of the drug in medicine should speak in its favor, but many patients wonder whether Corvalol is harmful to health and whether its use in treatment is always justified. To answer this question, you need to consider all the positive and negative aspects of this product.

Composition and effect of the drug

The release forms of this drug are tablets and drops. Drops have always been the most popular since the times of the Soviet Union. Speaking about the benefits and harms of Corvalol, you need to familiarize yourself with its composition. It includes ethyl bromizovalerate, phenobarbital, sodium hydroxide, peppermint oil, purified water.

Corvalol in drops is a colorless liquid with a specific pungent odor. The first two ingredients in the product have a calming and antispasmodic effect, relieve excitement and nervousness, provide strong and restful sleep. Peppermint extract dilates blood vessels, including those in the heart muscle, and has a positive effect on intestinal motility.

The components of the drug are optimally combined and complement each other’s action. The use of Corvalol is indicated in the following cases:

• increased irritability, excitability, anxiety;
• insomnia due to emotional experiences;
• tachycardia;
• the presence of spasms in the gastrointestinal tract;
• high blood pressure in the early stages of the disease.

It would seem that the benefits of the medicine are undeniable, but one cannot help but note a rather impressive list of contraindications for use.

There are frequent cases of individual intolerance to individual components of the product. In this case, Corvalol can pose a danger to the body. Doctors do not recommend Corvalol to patients with kidney and liver failure, as well as those with low blood pressure. In the latter case, Corvalol can bring the pressure to a critical point.

Pregnant women should be especially careful when taking the drug. Phenobarbital provokes the occurrence of hypoxia and irreversible disorders in the central nervous system of the unborn child. Corvalol is especially dangerous in the first three months of pregnancy. Thus, its use is permissible only in extreme cases and should be under the supervision of a doctor.

Children under 12 years of age can experience harm from Corvalol. Its use is possible only if the child has suffered severe moral experiences and traumas. But even with such a diagnosis, taking Corvalol should not be long-term and should be replaced with an analogue over time.

The dosage is of great importance when taking Corvalol. Since many people perceive the drug as a harmless remedy, the number of drops may not be controlled. Before deciding whether to use Corvalol as a medicine, you must determine the permissible dosage with your doctor. Otherwise, taking the drops may lead to an overdose.

Overdose and side effects

To have a clear idea of ​​why Corvalol is dangerous, you need to know the symptoms that occur during overdose and poisoning with this drug. The dangerous dose of the medicine is 150 drops, but in elderly people, weakened patients and children under 12 years of age, poisoning can occur with smaller doses.

There are three forms of poisoning: mild, moderate and severe intoxication. With a slight overdose, general weakness, confusion and drowsiness of the patient are noted. The patient's condition does not require any treatment and stabilizes after the drug wears off.

With moderate to severe poisoning, the patient experiences the following symptoms:

• muscle weakness;
• a sharp drop in blood pressure;
• dilated pupils;
• pathological sleepy state, the patient cannot be awakened;
• loss of consciousness;
• wheezing in the lungs;
• cyanosis of the skin of the face;
• disruptions in the functioning of the cardiovascular system.

In severe cases of intoxication, coma and even death are possible.

With the correct dosage of the drug, side effects occur very rarely and are of a mild nature. There is dizziness, general weakness, and daytime drowsiness.

Corvalol tincture is often used as a drug to eliminate hangover symptoms. Since alcohol itself causes rapid heartbeat, muscle weakness and increased excitability, in combination with Corvalol these symptoms only worsen.

The simultaneous use of Corvalol with tranquilizers and sedatives is also dangerous and extremely undesirable. A double dose of medication causes a negative reaction in the body.

Addiction and dependence on Corvalol

Phenobarbital and ethyl bromoisovalerate may be considered narcotic drugs. With regular use of Corvalol as a calming and sedative, the patient quickly becomes accustomed to the drug. One can speak of a certain degree of addiction even after two or three weeks of regular use of the drug.

Gradually, the standard dose ceases to produce the desired effect, which leads to the need to increase the dose, which, in turn, causes risks of deterioration in health. Subsequently, the drug accumulates in the body, so even a normal dose can cause phenobarbital poisoning.

It should be noted that sleep induced by a significant dose of Corvalol is often restless and does not bring a feeling of vigor upon awakening.

The harm from Corvalol also lies in the development of addiction to the drug. The patient feels chronic fatigue, is in a depressed, apathetic mood, speech and concentration may suffer.

Help with poisoning

If the symptoms of poisoning are minor, the patient needs gastric lavage. After the procedure, it is advisable to take one of the sorbents: activated carbon, smecta. Activated carbon prevents the absorption of toxic substances into the blood and accelerates their elimination from the body. It is better to take the product in the form aqueous solution. To do this, the tablet must be crushed and mixed with 100 ml of boiled water at room temperature. It is possible to use white activated carbon.

In case of poisoning, cleansing enemas are recommended. The victim must be provided with plenty of fluids; warm, sweet tea is better than other drinks. It is necessary to bring it back to normal low blood pressure and replenish lost glucose reserves.

At mild degree poisoning, the listed measures are usually sufficient. In case of moderate and severe poisoning, calling an ambulance should be a mandatory measure.

If the patient is unconscious, he is laid on a hard surface, belts and belts are loosened, and all jewelry that restricts movement and prevents free access of air is removed. Before doctors arrive, it is necessary to monitor the patient’s pulse. In case of severe poisoning, cardiac massage and artificial respiration are required.

To stabilize the condition in case of Corvalol poisoning, it is necessary intravenous administration antidote drug - bemegride. In most cases, moderate and severe forms of poisoning are treated in a hospital setting. The patient will need the help of a therapist and gastroenterologist. Treatment in specialized institutions involves the administration of glucose, sodium chloride, plasma and diuretics. If there is a significant concentration of phenobarbital in the blood, hemodialysis may be necessary.

Consequences of corvalol poisoning

Severe poisoning can have further complications for the body. Subsequently, allergic reactions on the skin may occur in the form of rashes, burning and itching. Pathologies of the liver and kidneys, disturbances in the functioning of the central nervous system, and a high risk of heart attack and stroke are also common.

Severe poisoning in a child can even be fatal.

The benefits and harms of Corvalol should be taken into account when choosing a dosage. For neurological diseases, the number of drops should not exceed 15-20, for nervous conditions - 10-15, to relieve heart pain - up to 40 drops. The number of doses should not exceed 3 times a day.

Careful adherence to the dosage of the medicine, preliminary consultation with a doctor, careful use of the drug will contribute to the effective action of Corvalol without negative consequences for the body.