Instructions for use of Troxevasin tablets (capsules) - price, reviews and analogues. Troxevasin capsules - instructions for use Troxevasin tablets official instructions for use

Tradename: TROXEVAZIN ®

International nonproprietary name:

troxerutin

Dosage form:

capsules

Description: hard cylindrical gelatin capsules No. 1, body - yellow, cap - yellow. Capsule contents: yellow to yellow-green powder.

Compound:

One capsule contains:
Active substance: troxerutin 300 mg.
Excipients: lactose monohydrate, magnesium stearate.
Capsule shell: capsule body - quinoline yellow dye (E 104), sunset yellow dye (E110), titanium dioxide (E 171), gelatin; capsule cap - quinoline yellow dye (E 104), sunset yellow dye (E 110), titanium dioxide (E 171), gelatin.

Pharmacotherapeutic group:

venotonic and venoprotective agent

ATX code C05CA04

Pharmacological properties.

An angioprotective agent that acts primarily on capillaries and veins.

Reduces pores between endothelial cells by modifying the fibrous matrix located between endothelial cells.

Inhibits aggregation and increases the degree of deformation of red blood cells; has an anti-inflammatory effect.

In chronic venous insufficiency, Troxevasin ® reduces the severity of swelling, pain, cramps, trophic disorders, and varicose ulcers. Relieves symptoms associated with hemorrhoids - pain, itching and bleeding.

Due to the beneficial effect of Troxevasin ® on the permeability and resistance of capillary walls, it helps slow down the development of diabetic retinopathy. In addition, its effect on the rheological properties of blood helps prevent microthrombosis of retinal vessels.

Pharmacokinetics

After oral administration, absorption is about 10 - 15%. Maximum plasma concentrations are reached on average 2 hours after administration; therapeutic plasma levels will remain for 8 hours. Metabolized in the liver, partially excreted unchanged in urine (20-22% of the dose taken) and bile (60-70% of the dose taken).

Indications for use

Chronic venous insufficiency, postphlebitic syndrome, trophic disorders in varicose veins and trophic ulcers. As auxiliary treatment after sclerotherapy of veins and removal of varicose nodes. Hemorrhoids (pain, exudation, itching and bleeding).

Venous insufficiency and hemorrhoids during pregnancy, starting from the second trimester.

As an adjuvant treatment of retinopathy in patients diabetes mellitus, arterial hypertension and atherosclerosis.

Contraindications. Hypersensitivity to rutosides or other components of the drug. Pregnancy (1st trimester). Gastric ulcer and duodenum, chronic gastritis in the acute phase, childhood up to three years (solid dosage form).

Carefully should be used (long-term use) when renal failure, children's age from 3 to 15 years (see section "Special instructions").

Use during pregnancy. Troxevasin ® should be used during pregnancy (II and III trimesters) and during lactation if the expected benefit for the mother prevails over possible risk for the fetus and child.

Directions for use and doses

Inside, during meals; The capsules are swallowed whole with a sufficient amount of water. At the initial stage of treatment, 1 capsule (300 mg) is prescribed 3 times a day.

The effect usually develops within 2 weeks, after which treatment is continued at the same dose or reduced to the minimum maintenance dose of 600 mg, or suspended (the achieved effect persists for at least 4 weeks). The course of treatment averages 3-4 weeks, the need for longer treatment is determined individually.

For diabetic retinopathy, 0.9 - 1.8 g/day is prescribed.

Side effect:

allergic reactions (eg skin rash), nausea, diarrhea, heartburn, headache, "flushes" of blood to the face, erosive and ulcerative lesions gastrointestinal tract. They disappear quickly after stopping treatment.

Overdose. In case of overdose, it may appear the following symptoms: excitement, nausea, headache, flushing of the face. In case of overdose, patients should rinse their stomach, take Activated carbon, if necessary, begin symptomatic treatment.

Interaction with other drugs. The effect is enhanced by simultaneous intake of ascorbic acid.

Special instructions. If the severity of the symptoms of the disease does not decrease during the period of use of the drug, you should consult your doctor. Taking the drug does not affect motor and mental reactions, does not interfere with driving or operating machinery. There is insufficient experience with the use of the drug in children under 15 years of age, which requires caution when using it.

Release form.

Capsules 300 mg. 10 capsules in a PVC/aluminum foil blister, 5 blisters in a cardboard box along with instructions for use.

Storage conditions.

In a dry place, protected from light, at a temperature not exceeding 25°C.

Keep out of the reach of children!

Best before date.

Do not use after expiration date.

Conditions for dispensing from pharmacies.

Over the counter.

Manufacturer:

Balkanfarma-Razgrad AD, April Uprising Blvd., 68, 7200 Razgrad, Bulgaria

Representative address:

LLC "Aktavis" 127018, Moscow, st. Suschevsky Val, 18,

Troxevasin capsules are used to treat all forms of varicose veins, acute and chronic hemorrhoids, vascular disorders in diabetes mellitus and some other diseases and conditions. The main effect of this drug is its positive effect on the function of small blood vessels - capillaries.

Troxevasin in capsules - how it works


Each capsule of troxevasin contains 300 mg of the active ingredient troxerutin. Troxerutin is an active semi-synthetic bioflavonoid - an analogue of natural rutin. Just like rutin, it belongs to the group of vitamins P and has a beneficial effect on capillaries and superficial veins. Troxevasin works especially effectively “in combination” with ascorbic acid - it enhances the strengthening effect of ascorbic acid on the walls of the veins, as it prevents its oxidation (antioxidant effect).

When taking capsules (troxevasin tablets are not available, but some mistakenly call capsules tablets) orally, the active active substance is slowly and not completely absorbed into the blood and gradually strengthens the walls of blood vessels, making them less permeable and thus preventing swelling.

In case of thrombophlebitis of the superficial veins, troxevasin reduces inflammatory processes in the walls of the veins and prevents platelet aggregation - gluing them together to form large conglomerates, which later form the basis of blood clots. Increasing the tone of the smooth muscles of the veins is the prevention of stagnation of blood in them, edema, inflammation and thrombosis.

Troxevasin also has a positive effect when there is stagnation of venous blood in the area anus and rectum - chronic and acute hemorrhoids. Taking Troxevasin capsules helps prevent the transition of chronic hemorrhoids to acute ones. If acute hemorrhoids have already begun (usually they occur with thrombosis of the rectal veins), then troxevasin significantly alleviates the condition of patients.


Who will benefit from troxevasin capsules?

Any form of venous insufficiency is an indication for the use of troxevasin. Venous insufficiency occurs when the tone of the vein walls and the functioning of the intravascular valves, which normally prevent the reverse flow (from top to bottom) of blood, are disrupted. This leads to stagnation of blood, dilation of the veins of the extremities, and swelling. Swollen soft tissues of the extremities compress the arteries that carry blood to soft tissues in the affected area, which causes progressive trophic disorders in them in the form of trophic dermatitis and trophic ulcers.

In this case, Troxevasin is used in long courses (from a month to several months as prescribed by a doctor) - this tones the walls of the veins and causes a gradual restoration of impaired venous outflow. Trophic disorders of soft tissues also gradually disappear.

For chronic hemorrhoids, which can last a long time with minimal manifestations in the form of periodically appearing bloody discharge. Bloody discharge - it is important to exclude pathology , TroxevasinTroxevasin - will help if problems arise with the veins


prevents the appearance of blood clots in the veins of the rectum and anus and promotes the gradual normalization of venous outflow. If the chronic course of hemorrhoids is complicated by vein thrombosis or strangulation hemorrhoids, then the process becomes acute. Troxevasin in this case relieves inflammation and swelling, which leads to a decrease in pain. The antithrombotic effect of troxevasin prevents the progression of the disease and tissue necrosis (death).

For diabetes mellitus Diabetes mellitus is a terrible and incurable disease small ones are often affected blood vessels feet, which leads to progressive trophic changes in the tissues of the feet, up to gangrene. Troxevasin in this case is prescribed in maximum dose for a long period of time.

During pregnancy, women often develop venous insufficiency in the form of varicose veins and hemorrhoids. Troxevasin capsules can be used after the first 12 weeks of pregnancy, but only if its use is vital for the woman. Of course, it cannot be used independently, only as prescribed by an obstetrician-gynecologist or a antenatal clinic therapist.


Side effects and contraindications

When taking troxevasin in capsules there are rarely side effects However, sometimes heartburn, nausea, and loose stools occur. Loose stools – indigestion. , headaches, rushes of blood to the head, erosions and ulcers on the mucous membranes of the stomach and intestines.

Troxevasin in capsules should not be used if the patient’s body is hypersensitive to it, in the first 12 weeks of pregnancy, or with exacerbation of erosive and ulcerative processes in the gastrointestinal tract. Troxevasin is prescribed with caution and in short courses for renal dysfunction.

Galina Romanenko

www.womenhealthnet.ru

Active ingredient of the drug, pharmacological action

The main active ingredient of capsules and ointments is Each capsule contains 300 milligrams of troxerutin, and in the ointment the concentration is 2%, that is, in one gram there are 20 milligrams of the active substance.

Troxerutin is a semi-synthetic derivative of rutin. This bioflavonoid has a venotonic, antioxidant, anti-edematous, anti-inflammatory, and angioprotective effect.

The result of its use is a decrease in capillary fragility and permeability, as well as a decrease in pain and inflammatory processes in nearby tissues. Microcirculation improves, as a result of which normal tissue nutrition is restored.

Indications for use

  1. Varicose veins. It is advisable to use a combination of capsules for internal use + ointment for external use.
  2. Chronic venous insufficiency (swelling, pain and heaviness in the lower extremities).
  3. Retinopathy in diabetes mellitus.
  4. Trophic ulcers.
  5. Thrombophlebitis. Use ointment and capsules as an addition to complex treatment.
  6. Periphlebitis.
  7. Varicose dermatitis.
  8. Injuries without damage to the integrity of the skin (bruises, fractures, bruises). The use of troxivazin in the form of an ointment is effective.
  9. Hemorrhoids, with or without nodes.
  10. With an increase in capillary permeability ( viral infections, flu, scarlet fever, etc.).

Contraindications

As a rule, the drug is well tolerated by patients. But anyone pharmacological agent there are some contraindications.

  1. Stomach or duodenal ulcer.
  2. Chronic gastroduodenitis or gastritis, during exacerbation.
  3. Chronic renal failure.
  4. In case of individual intolerance to at least one of the components of the drug.
  5. Troxevasin ointment should not be used if the integrity of the skin is compromised.
  6. First trimester of pregnancy.

Side effects

Adverse effects while taking the drug are expressed in the form of erosive and ulcerative processes in the gastrointestinal tract, in the case of using capsules. And also skin allergic reactions when applying ointment.

Instructions for use of Troxevasin

It is recommended to take one capsule, two or three times a day, always with food, to prevent the irritating effect of troxerutin on the stomach. The daily dose should not exceed 900 milligrams per day and is prescribed for a maximum of two weeks.

Subsequently, the patient switches to a maintenance dosage of 200-400 mg for 2 or 3 weeks. For the treatment of retinopathy, the recommended dosage is 300-600 mg three times a day.

Improvement occurs only with regular application of the product long time. In order to enhance the therapeutic effect, it is advisable to take troxevasin capsules simultaneously.

After a week of treatment, the first signs of the drug’s effects are noticeable, in the form of decreased swelling, pain, and itching. In the absence of positive dynamics during treatment, or deterioration of the initial clinical symptoms, you should stop taking the drug immediately and consult an experienced doctor.

To improve the effect of troxevasin, parallel administration is required ascorbic acid. Using toxevasin ointment it is necessary to prevent access sun rays to the treated areas of skin. Store medications in a dark, cool, dry place.

Cost of Troxevasin

Troxevasin is a fairly expensive drug. The pricing policy depends on the manufacturer (they use raw materials of different quality), as well as the number of capsules in the package or milliliters in the tube.

On average, the price in Russian pharmacies fluctuates:

  • for capsules No. 100 in a package from 550 to 650 rubles;
  • for capsules No. 50 in the range of 280-380 rubles;
  • for 2% ointment weighing 40 grams from 150 to 210 rubles;
  • for Troxivazin Neo gel from 230 to 250 rubles.

Why is it worth looking for analogues?

The pharmacological industry produces a large number of troxevasin analogues, and most of them are not inferior in quality.

But choosing more cheap drug, be sure to consult your doctor because its effects may be slightly different than expected.

Reasons why you should look for analogues:

  1. Lower price.
  2. Lack of the expected effect from the use of this drug.
  3. No contraindications for use.

Analogs

The pharmacy chain offers a fairly wide range of similar drugs medicines.

These include:


ovarikoze.com

Composition and release form

"Troxevasin" is produced by the Bulgarian pharmaceutical company for treatment pathological processes in venous vessels.


Troxevasin ointment belongs to the group of venotonic agents

The drug can be purchased at the pharmacy in two forms:

  • gel;
  • capsules.

Despite the fact that the official form of release is gel, the drug for external use is often called an ointment. Troxevasin ointment is most often used for treatment. Modern form The drug is "Troxevasin Neo". Medicines differ from each other in the content of active components.

The composition of a regular gel includes troxerutin as an active ingredient and additional substances:

  • trolamine;
  • benzalkonium chloride;
  • disodium dihydrate;
  • carbomer.

"Troxevasin Neo" contains a combination of three active components: troxerutin, dexpanthenol and sodium heparin.

Pharmacological properties

Troxevasin ointment is a vasodilating anti-inflammatory agent with a decongestant effect. The mechanism of action of the drug is aimed at increasing the tone and strengthening the vascular walls of veins and capillaries, as well as eliminating inflammation and improving blood circulation.


Due to the properties of this medicine, it is used to treat vein diseases, and also helps to quickly restore tissue after bruises or sprains

As a result of application:

  • the fragility and permeability of capillaries is reduced;
  • the tone and elasticity of all blood vessels increases;
  • vascular walls become denser.

Regarding blood circulation:

  • microcirculation is normalized;
  • Stagnation of blood flow is eliminated due to blood thinning.

Restoring the functions of the circulatory system allows you to improve tissue nutrition, prevent inflammatory processes and accelerate the regeneration process in the body.

Indications


Troxerutin helps restore the elasticity of vascular tissue, which prevents their deformation and fragility

Troxevasin is used to eliminate pathologies:

  • superficial forms of phlebitis in the acute phase;
  • varicose veins;
  • swelling of soft tissues;
  • post-varicose syndrome;
  • microangiopathy (diabetic);
  • vascular disorders after radiation therapy;
  • chronic venous insufficiency;
  • peptic ulcer of the skin (against the background of varicose veins).

In addition to the main indications related to venous insufficiency and blockage of blood vessels, the instructions recommend using Troxevasin ointment for hemorrhoids, muscle and joint damage (for example, bruises). Troxevasin ointment during pregnancy is recommended from the second trimester for the treatment of hemorrhoids and varicose veins of the legs.

Contraindications

The product has contraindications, which are described in the instructions. The drug is not prescribed if the patient has:

  • chronic gastritis;
  • gastrointestinal ulcers;
  • renal failure;
  • allergies to the active substance and other components of the composition.

You should not use this product if you have hypersensitivity to the components that make up the ointment.

In accordance with the recommendations regarding Troxevasin ointment, the instructions for use warn of a contraindication for application if there are open wounds, purulent and infectious lesions on the patient’s skin (at the site of application). It is not advisable to use the ointment for women in the first trimester of pregnancy. The drug causes an adverse reaction in rare cases. Side effects occur in the form of dermatic skin lesions, urticaria and eczema.

Instructions

The gel is used externally only. Apply the medication to the affected area light movements, rubbing into the skin surface until the gel is completely absorbed.

Depending on the indications, the following recommendations should be followed:

  1. In case of vascular disease, the combined use of compression stockings is recommended.
  2. For hemorrhoids, you can make compresses with gel by applying a gauze swab with a medicinal composition to the anus.
  3. In case of soft tissue injury, simply apply the gel.

The ointment is used morning and evening, applying and gently rubbing until the product is completely absorbed.

"Troxevasin" should be used regularly - twice a day for at least one month. It is recommended to determine the dosage regimen individually in consultation with your doctor.

special instructions

Troxevasin has special instructions described in the annotation.

  1. The effectiveness of the drug increases with joint use gel and capsules "Troxevasin".
  2. The composition can only be applied to whole skin.
  3. With accompanying infectious processes(internal) take vitamin C at the same time.
  4. Other vasodilators and blood-thinning medications (for example, acetylsalicylic acid) should not be used during gel therapy.

If all rules of use are followed, the risk of side effects is minimized, and the result of treatment occurs much faster.


With increased vascular permeability, it is recommended to use troxevasin ointment in combination with ascorbic acid

Analogs

“Troxevasin” is an effective medication that quickly combats the manifestations and consequences of varicose veins. However, the cost of the drug, as well as concomitant diseases that are a contraindication, may require the use of analogues for treatment.

Substitutes are selected depending on the composition, pharmacological properties and release forms. If the patient is prescribed Troxevasin ointment, it is recommended to replace it with a drug for external use.

Analogue of Troxevasin ointment:

  • "Troxerutin";
  • Heparin ointment;
  • "Troxevenol";
  • "Detralex";
  • "Venolife".

You should select an analogue together with your doctor. All special instructions must be taken into account, not just the price of the drug product.

Price and where to buy

In the event of the development of diseases associated with inflammation and damage to capillary walls, as well as veins, the recommended Troxevasin ointment can be purchased at a pharmacy without a prescription from a doctor.

In different pharmacy chains and depending on the manufacturer, the price for Troxevasin ointment may vary. The average cost of the drug is from 200 rubles.

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What is troxerutin

The active component of the drug involves the substance troxerutin, which acts as a synthetic substitute for rutin. This component is one of the representatives of the P vitamins and is part of certain plant families. This substance is a mixture of active components rutin, which helps reduce the permeability and fragility of capillaries, eliminates swelling and inflammatory processes.

This allows the drug to be used in the treatment of a large number of vascular pathologies, as well as during the recovery period after surgical interventions.

What pharmacological effects does the medicine have?

Troxevasin helps against varicose veins by providing the following therapeutic effects:

  1. Increased tone of the walls of blood vessels.
  2. Normalization of the process of resistance to reverse blood flow.
  3. Reducing oxidative processes in affected tissues, which in turn prevents the formation of trophic disorders.
  4. Promotes anti-inflammatory effects.
  5. Troxevasin enters the area of ​​the capillary walls, after which it has a preventive effect on the formation of blood clots and normalizes microcirculation in the area of ​​the affected limb.
  6. Since the drug has a tonic effect on the walls of blood vessels and veins, the gel can help restore the functional state of the deep veins.
  7. At the initial stage of development of varicose veins, the gel helps restore venous circulation.

After the patient applies the medicine, the gel quickly absorbs and penetrates deeply into the area of ​​the affected tissue and gradually reaches the vascular area. The use of the gel allows you to have a tonic effect on the capillaries, as well as prevent the development of stagnation and fluid accumulation in the soft tissue area.

It must be taken into account that the medicine helps if the patient follows all the necessary recommendations regarding its storage conditions. Troxevasin gel is produced in metal tubes, which should be stored in a dark place at room temperature. The drug should not be allowed to freeze.

Patients should understand what the ointment helps with. Direct indications for the use of the drug are the development of:

  • Varicose veins.
  • Symptoms of chronic venous insufficiency. This disease can manifest itself in the form of intense pain, swelling, the formation of a vascular pattern, convulsions, and a feeling of heaviness in the lower extremities.
  • Thrombophlebitis or periphlebitis. In this case, the use of the gel helps eliminate the inflammatory process in the area of ​​the walls of blood vessels and veins, and also prevents the formation of blood clots.
  • Dermatitis caused by varicose veins.
  • Trophic ulcers that can form due to circulatory disorders.
  • The ointment is also used in case of hematomas and bruises that occur after injections or as a result of injuries. In this case, the medicine is used as an ambulance. The gel can be used if there is no violation of the integrity of the skin.
  • Troxevasin can be used for preventive treatment in the autumn and spring seasons. This helps strengthen blood vessels and stops the further development of the disease.

Troxevasin is widely used in the treatment of patients at risk: for example, people with a history of diabetes mellitus.

If necessary, the drug is widely used in the treatment of women expecting the birth of a baby. This is due to the fact that, according to research results, it was not revealed negative impact troxerutin on the process of fetal development. The drug is used in this case only on the recommendation and under the supervision of the attending physician.

The manufacturer indicates that Troxevasin ointment begins to help if used regularly for at least several months.

The manufacturer of the drug indicates that this ointment may contribute to the development of unwanted adverse reactions in the form of allergic manifestations at the site of application of the medicine, as well as dermatitis and eczema. The described side effects develop in isolated cases. This side effect requires immediate cessation of use of the ointment and consultation of the attending physician. In the future, it may be necessary to prescribe symptomatic therapy and select a replacement drug.

The gel is highly tolerable to the skin and does not provoke the development of sensitizing side effects. This allows the drug to be used during the period of time with the greatest solar activity without harm to the patient’s body.

It should also be taken into account that the use of ointment is contraindicated if the patient has a history of intolerance to rutin derivatives. Also, the drug should not be used if the skin is damaged; Troxevasin ointment should not be allowed to come into contact with the mucous membranes.

How to use the drug correctly?

You should remember how to use Troxevasin correctly and that this ointment effectively helps on initial stage development of varicose veins, chronic venous insufficiency and other diseases. In the future, the use of the ointment must be combined with the internal administration of Troxevasin capsules.

Troxevasin ointment should be applied to the area of ​​the skin located above the lesion and lightly rubbed in with light massage movements. Such manipulations must be carried out in the morning and evening. The duration of therapy using Troxevasin ointment can be long: from several months to six months. It may be recommended to take short breaks between courses of treatment.

Troxevasin helps better if used in conjunction with other groups of drugs. The appointment should be made by a qualified phlebologist after performing the necessary examination and in-person examination of the patient.

This drug is known a large number people, however, it is recommended to refrain from self-medication using the described gel. The drug can be purchased at any pharmacy without presenting a prescription. However, you should remember that only a doctor will help you choose the appropriate dosage and prescribe the exact duration of use of the medicine. If necessary, he will be able to select concomitant treatment.

Therapy should be carried out under the constant supervision of a doctor who can assess the degree of positive effects of the drug. If after several months of regular use the gel does not have the expected therapeutic effect, the treatment regimen will be reviewed and supplemented. The main goal of treatment is to stop the progression of the pathology and prevent the development of possible vascular complications.

The use of any medications, including gel, can be combined with the use of compression stockings, as well as performing a special set of exercises therapeutic exercises. In addition, the patient will be advised to adjust their usual diet and give up bad habits, especially smoking.

varikoznic.ru

Instructions for use

Drugs for the treatment of varicose veins are prescribed for use by a phlebologist and have a therapeutic and preventive effect. The drug "Troxevasin" has proven itself from the best side.

Description

Ointment, 2% concentration, yellow to beige. Applied externally

The active substance rapidly penetrates the outer layer of the epidermis when applying ointment to the affected area. After 30 minutes, the component is detected in the dermis, after 2-5 hours - in fatty tissue. This action ensures the accumulation of active components in tissues.

The ointment has good epidermal tolerance and does not have a sensitizing effect. The use of the ointment is recommended for patients both in the initial and late stages of the disease.

“Troxevasin” is a flavonoid characterized by P-vitamin activity. The rutin derivative has a tonic effect on the veins and is a venoprotector. Means has anti-edematous, anti-coagulant, anti-inflammatory effects, antioxidant.

Composition, release form, dispensing in pharmacies and price.

Release form:

  • Ointment (gel) in aluminum tubes, 40.0 g.
  • Ointment (gel) in plastic tubes, 40.0 g.

Terms of sale from pharmacy chainsover the counter

Price A 40 g tube is available for 135 rubles.

Best before date

  • Ointment in an aluminum tube – 5 years.
  • Ointment in a plastic tube – 24 months.

Storage conditions: dry place, isolated from light, temperature 25°C or less. Do not freeze.

Indications for use

  • Varicose veins.
  • Swelling and pain in the legs, a feeling of permanent heaviness, fatigue - symptoms of venous insufficiency in chronic form.
  • Spider veins and spider veins.
  • Cramps.
  • Parestensia is a sensitivity disorder that is characterized by the development of numbness, tingling, and “goosebumps.”
  • Thrombophlebitis is an inflammatory process that affects the venous walls, accompanied by the formation of a blood clot (thrombus).
  • Periphlebitis is inflammation of the tissues surrounding the vein.
  • Varicose dermatitis - develops over dilated and poorly functioning veins.
  • Swelling and pain of traumatic origin.

Contraindications and dosage

  • High sensitivity to the components of the ointment due to individual intolerance.
  • Violation of the integrity of the epidermal layer. The drug should not be applied to areas where the skin is damaged.

Product for external use. The medication is applied to the affected area twice daily, morning and evening. The ointment is gently rubbed until naturally absorbed. If there is a corresponding need, The gel is applied under bandages and elastic stockings.

Overdose and side effects

Thanks to the external method of application There is no danger of overdose. In case of overdose, be sure to see a doctor. Peritoneal dialysis is performed according to indications.

Such manifestations are extremely rare.

  • Hives,
  • Eczema,
  • Dermatitis and less severe skin rashes.

special instructions

Ointment "Troxevasin" during pregnancy and lactation

  • The drug is used in the second and third trimester strictly as prescribed by the attending physician.
  • The ointment is applied to the affected areas according to the instructions, twice daily (morning and evening).
  • Indications for use during pregnancy: varicose veins, swelling of the legs, hemorrhoids.
  • The duration of use of the ointment is determined by the doctor.
  • At breastfeeding is not prescribed, or the issue of completely abolishing breastfeeding is being decided.

Ointment "Troxevasin" for children

According to indications, the drug is prescribed in childhood:

  • In order to improve blood circulation.
  • For treating areas after injections or vaccinations in case of compaction.
  • For the treatment of bruises, sprains, hematomas.
  • A drug It is recommended to combine it with taking Troxevasin capsules (tablets) to enhance the therapeutic effect. If the symptoms of the disease worsen and last more than seven days, you should consult a doctor.
  • The medication does not affect the ability to drive machinery and vehicles.
  • There are no data on interactions with other drugs.

Analogs

"Troxerutin." The drug is applied twice a day, mainly in the morning and evening hours. The ointment is rubbed into the affected areas with light movements until completely absorbed.

Application:

  • Venous insufficiency, mostly chronic.
  • Ulcerative lesions of the legs.
  • Varicose veins
  • Thrombophlebitis is superficial.
  • Hemorrhoids.
  • Hematomas and edema.
  • Hemorrhagic diathesis, accompanied by high capillary permeability.
  • Capillarotoxicosis, including influenza, measles, scarlet fever.
  • Retinopathy.
  • Side effects of radiation therapy affecting blood vessels.
  • Prevention after surgery on veins.

Differences and features:

  • The drug is not prescribed to persons under 18 years of age.
  • The ointment does not disrupt the natural physiology of the skin.
  • pH level medication similar to epidermal.

Price packaging – 250 rubles.

"Troxevenol". The ointment is applied to the affected areas twice a day, mainly in the morning and evening hours.

Application:

  • Varicose veins.
  • Thrombophlebitis, mainly superficial.
  • Trophic ulcers.
  • Hemorrhoids.

Features and differences

  • The drug has high bioavailability.
  • The active component - troxerutin - quickly accumulates in the body in maximum concentration and has a high therapeutic effect.

Price 40 g tubes cost 90-115 rubles.

Instructions for use:

Troxevasin is an angioprotective drug with anti-edematous and anti-inflammatory effects, used in the treatment of venous insufficiency, varicose veins, etc.

Pharmacological action of Troxevasin

The active component of Troxevasin is troxerutin, which exhibits P-vitamin activity and is a semi-synthetic derivative of rutin with a predominant trihydroxyethylrutoside. The drug reduces capillary fragility and has angioprotective, venotonic, antioxidant and anti-inflammatory effects.

Release form of Troxevasin

The drug Troxevasin is produced in the form of a gel for external use and in capsules. According to the instructions, one hard, cylindrical, yellow gelatin capsule of Troxevasin contains 300 mg of troxerutin, 47 mg of lactose monohydrate and 3 mg of magnesium stearate. The shell contains 0.9% quinoline yellow dye E104, 3% titanium dioxide E171, 100% gelatin and 0.039% sunset yellow dye E110.

The composition of 2% Troxevasin gel according to the instructions includes 20 mg of troxerutin, 6 mg of carbonara, 0.5 mg of disodium ethylenediaminetetraacetic acid, 1 mg of benzalkonium chloride, 7 mg of triethanolamine and 965.5 mg of purified water.

Analogues of Troxevasin

Analogs of Troxevasin based on the active component are:

  • Troxerutin Vetprom;
  • Troxerutin-MIC;
  • Troxevenol;
  • Troxerutin Vramed;
  • Troxerutin Zentiva.

Analogues of Troxevasin according to their belonging to one pharmacological group and the effect provided include:

  • Askovertin;
  • Askorutin D;
  • Vasocket;
  • Venolek;
  • Venoruton;
  • Diosmin;
  • Rutin;
  • Phlebodia 600;
  • Yuglanex.

Indications for use of Troxevasin

According to the instructions, Troxevasin is prescribed for hematomas, dislocations, bruises, sprains, contusions, muscle spasms, and also in cases:

  • Side vascular effects of radiation therapy;
  • Post-varicose syndrome;
  • Varicose veins;
  • Acute superficial thrombophlebitis and periphlebitis;
  • Diabetic microangiopathy;
  • Chronic venous insufficiency;
  • Ulcerative skin lesions and dermatitis against the background of varicose veins;
  • Hemorrhoids;
  • Varicose ulcers.

In case of hemorrhoids and venous insufficiency during pregnancy, Troxevasin is prescribed from the second trimester. The medicine is also used as additional treatment for vascular disorders of the retina in patients with arterial hypertension, diabetes mellitus and atherosclerosis.

How to use Troxevasin

Based on the instructions, Troxevasin capsules are administered orally during meals. The dosage of the product is 2 capsules once a day, with maintenance therapy the dose is 1 capsule per day for a month.

Troxevasin in the form of a gel is applied with light massaging movements to the affected areas of the skin, twice a day, morning and evening, until complete penetration into the skin. The medication is used regularly over a long period of time, applied exclusively to an intact surface.

Contraindications

According to the instructions, Troxevasin is contraindicated for use in cases of chronic gastritis, hypersensitivity to the drug and its components, peptic ulcer stomach and duodenum. The medication is prescribed with caution in cases of renal failure. During pregnancy, Troxevasin is contraindicated for use in the first trimester.

Side effects of Troxevasin

According to reviews, the use of Troxevasin leads to complications extremely rarely; cases of drug overdose are unknown. In rare cases, Troxevasin reviews cause dermatitis, eczema and urticaria. If the medicine causes other side effects not described above, you should immediately consult a doctor.

Storage conditions

In accordance with the instructions, Troxevasin in capsules is dispensed only as prescribed by a doctor, in the form of a gel without a prescription. The medicine must be stored in a dry, ventilated room, protected from light, at a temperature of 15 to 25°C.

Troxevasin is medicinal product from the clinical and pharmacological group of angioprotectors, venous circulation correctors. To increase the effectiveness of therapy for manifestations of varicose veins, it is recommended to combine the use of a local form with capsules for oral administration. If there is no positive dynamics with prolonged use of the drug, you should stop taking it and consult a specialist.

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    General information about the drug

    The description of the drug is presented in the table:

    The drug is available in the following varieties:

    Dosage form Active ingredient concentration Release form
    Hard gelatin capsules for oral administration, cylindrical in shape and yellow in color.

    The contents of the capsules are powder with a yellow or yellowish-green color. It is acceptable to have lumps that disintegrate when pressed.

    This dosage form sometimes mistakenly called tablets

    		300 mg per 1 capsuleBlisters of 10 capsules; 5 or 10 blisters in a cardboard box
    A topical gel (sometimes erroneously called an ointment) that ranges in color from yellow to light brown2% (20 mg) per gramAluminum or plastic tubes containing 40 g of dosage form

    Complete analogues of the drug are:

    • Troxerutin, which is also available in the form of capsules containing 300 mg of active substance, and 2% gel.
    • Gel Troxevenol.

    Pharmacological properties

    Troxevasin belongs to the pharmacological group of drugs used for the treatment of venous circulation disorders. It is an angioprotector.

    The action of troxerutin extends mainly to veins and capillaries. This active substance causes a reduction in the distances between endothelial cells, inhibits aggregation and provokes an increase in the ability of red blood cells to deform. Troxerutin also has an anti-inflammatory effect.

    In the presence of chronic failure venous circulation Troxevasin reduces the severity of swelling, fights pain, relieves cramps, prevents trophic disorders and promotes the healing of existing varicose ulcers.

    Troxevasin also tends to relieve symptoms that are manifestations of hemorrhoids - pain, itching, bleeding.

    Due to its positive effect on the permeability of capillary walls, Troxevasin helps slow the progression of diabetic retinopathy, and its beneficial effect on the rheological quality of blood prevents microthrombosis of the vessels of the retina, reducing the degree of platelet adhesion to the surface vascular wall.

    Pharmacokinetics

    After oral administration, absorption of the active substance is about 10-15%. The highest concentration in the blood plasma is achieved 2 hours after administration, the therapeutic dose (effective level of troxerutin in the blood) is maintained for 8 hours.

    Troxerutin is metabolized in the liver. Elimination - partially unchanged in urine.

    When applied topically, after applying the gel to the affected area, troxerutin quickly penetrates the epidermis, and after half an hour its presence is registered in the dermis. For penetration of the active substance into the subcutaneous fatty tissue it takes from 2 to 5 hours.

    Indications

    Indications for the use of the drug Troxevasin are the following pathological conditions:

    • chronic insufficiency of venous circulation;
    • postphlebitic syndrome;
    • trophic disorders in tissues that exist against the background of varicose veins;
    • trophic ulcers on the legs;
    • varicose veins and hemorrhoids, accompanied by pain, exudation, itching, bleeding;
    • venous insufficiency, varicose veins veins and hemorrhoids during pregnancy (used starting from the second trimester);
    • retinopathy in patients suffering from diabetes mellitus and arterial hypertension.

    The medicine is also used in the treatment after sclerotherapy of veins and removal of varicose veins, for atherosclerotic vascular lesions as an auxiliary component of therapy. In addition, indications for the use of Troxevasin gel are periphlebitis, varicose dermatitis, pain and swelling of soft tissues of a traumatic nature resulting from bruises, sprains, and other injuries.

    Dosage regimen

    Troxevasin capsules are intended for oral administration during meals. They should be taken whole, without breaking their integrity, with plenty of water.

    For the initial stages of therapy, a dosage of 300 mg (1 capsule) three times a day is suitable. The effect develops over 2 weeks, after which treatment should be continued at the same dosage or reduced to the minimum maintenance dose - 600 mg per day (1 capsule 2 times a day).

    If therapy is suspended at this stage, the achieved effect lasts for at least 4 weeks.

    The duration of the course of treatment averages from 3 to 4 weeks; the need for a longer course is determined individually by the attending physician.

    According to the instructions for use for diabetic retinopathy, the daily dosage is from 0.9 to 1.8 g per day.

    Troxevasin gel is intended for external use. It should be applied to the affected area twice a day: in the morning and in the evening, gently rubbing. If necessary, the gel can be applied under bandages or anti-varicose stockings. The success of therapy with the local form of Troxevasin depends on regular use over a long period.

    If there is no positive dynamics within 6-7 days of daily use of the gel or the disease worsens, you should consult a doctor.

Troxevasin (lat. Troxevasin) is a drug belonging to the group of angioprotectors. Its effect on blood vessels allows it to be used for the treatment of other diseases.

Features of the drug

Form

Troxevasin is available in two forms:

  • Gel(sometimes called ointment) for external use, yellow or light brown in color.
  • Capsules(tablets) cylindrical in shape in a yellowish hard shell.

This video will tell you about the use, release forms, and side effects of Troxevasin:

Composition of Troxevasin

1 g of the drug contains 20 mg of the main component - troxerutin. The auxiliary components are: edetate dihydrate, purified water, trolamine, benzalkonium chloride, carbomer.

Prices

The drug in the form of a gel can be purchased at a price of 220-240 rubles, in the form of capsules - from 360 rubles per pack.

pharmachologic effect

Pharmacodynamics

Troxevasin is a derivative of rutin and has the following actions:

  • Venoprotective;
  • Anticoagulant;
  • Antioxidant;
  • Venotonic;
  • Decongestant;
  • Anti-inflammatory.

In addition, the drug is distinguished by P - vitamin activity, improves the density of the walls of blood vessels, reduces the exudation of the liquid component of plasma and leads to a decrease in the adhesion of platelets to the walls of blood vessels.

Pharmacokinetics

After using the drug Troxevisin, the concentration of the active ingredient is 15%. The maximum value is observed after 2 hours from taking the capsules, and therapeutic effect lasts up to 8 hours.

Most of the drug taken (up to 70%) is excreted in the bile and partially (up to 22%) in the urine.

Indications

Troxevasin has the following indications for use:

  • Venous insufficiency in a chronic form, which manifests itself in the lower leg area, heaviness in the legs and other skin lesions;
  • Phlebothrombosis;
  • Retinopathy;
  • (to improve lymph circulation),
  • Capillarotoxicosis, developing against the background of measles, influenza and other viral diseases;
  • Phlebeurysm;
  • Side effects of a vascular nature that arose against the background of;
  • (to improve the elasticity of red blood cells),
  • Prevention after venous surgery.

A review of the use of Troxevasin is contained in this video:

Instructions for use

  • The drug is in capsule form It is recommended to take 1 capsule 2 times a day. A positive result is observed after 14 days, after which maintenance treatment is prescribed. It involves taking 1 capsule per day (300 mg) for the next 3-4 weeks. Capsules are washed down with plenty of water, and it is recommended to take the capsules during meals.
  • The drug is in the form of a gel also used 2 times a day (morning and evening), by applying to the affected areas of the skin. It is not recommended to get the gel on open wounds or mucous membranes.

Photos of Troxevasin

Children, newborns

There are no special instructions for the use of Troxevasin in children and newborns.

During pregnancy and lactation

In the second half of pregnancy, as well as during lactation, the drug can be used if the expected effect from it is higher than the risk to the fetus and baby.

Contraindications

Contraindications to the use of this drug are:

  • Individual sensitivity to one of its components;
  • Functional kidney disorders;
  • Exacerbation of gastritis.

Side effects

When using Troxevasin in the form of capsules or ointments, in rare cases manifestations (rash, rash) may occur, as well. These symptoms go away on their own after discontinuation of the drug.

special instructions

  • The gel is not recommended for use on open wounds and damaged areas of skin.
  • You should also avoid getting it on mucous membranes and eyes.

Interaction with other drugs and alcohol

  • In cases where the walls of blood vessels are more susceptible to absorption of the drug (measles, influenza, scarlet fever, etc.), it can be used in parallel with ascorbic acid. Vitamin C enhances the effect of the drug.
  • Using Troxevasin does not affect driving ability Vehicle and brain activity reactions.