We have selected real reviews about the drug Aminalon, which are published by our users. Most often, reviews are written by mothers of young patients, but they also describe their personal history of using the drug on themselves.

Indications for use

Atherosclerosis of cerebral vessels, cerebrovascular insufficiency (impaired memory, attention, speech; dizziness, headache), dynamic cerebrovascular accident, conditions after stroke and traumatic brain injury, alcoholic encephalopathy, dementia, mental retardation, endogenous depression, polyneuritis, children's cerebral paralysis, kinetosis.

Discussion of the drug Aminalon in the posts of mothers

In the USA and many other countries, it refers to dietary supplements, and not to drugs. $15 a jar for a month of use. In Japan, withdrawn from sale due to apparent ineffectiveness. 6. Nootropil, Piracetam, Phezam, Aminalon, Phenibut, Pantogam, Picamilon, Instenon, Mildronate, Cinnarizine, Mexidol - placebo drugs. 7. Wobenzym. Manufacturers claim that it heals, prolongs life and youth. You should not believe in a fairy tale about a miracle drug that has not been tested in experimental studies just because it is expensive. Drug companies invest hundreds of millions of dollars in testing a drug, even if there is little hope that it can be proven to be effective. One can only guess...

Aminalon is less purified and has more side effects. One composition is indicated. But we have no side effects. I wrote the result - it helps solve problems with blood flow and headaches. All. We were examined and there is kinking and thinning of the blood vessels. That's why they prescribed it along with electrophoresis...

Ropeptides, etc. - Cerebrolysin, Actovegin, solcoseryl, Cortexin, etc. 3. So-called “nootropic” drugs that “improve brain nutrition”: piracetam, aminalon, phenibut, pantogam, picamilon, etc. 4. Homeopathic remedies.5. A variety of herbal preparations, including valerian, motherwort, well-known to the population, as well as lingonberry leaf, honey...

Ropeptides, etc. - Cerebrolysin, Actovegin, solcoseryl, Cortexin, etc. 3. So-called “nootropic” drugs that “improve brain nutrition”: piracetam, aminalon, phenibut, pantogam, picamilon, etc.) are routinely prescribed to most patients diagnosed with PEP, but they SHOULD NOT be used in the treatment of children! They have not been adequately tested in neonates and young children, so their effectiveness and/or safety cannot be judged. The use of drugs with unproven effectiveness may, at best, be useless, and then it is a waste of time, which in many diseases, for example, epilepsy,...

Are they rewriting? Didn't you do an MRI? Our eldest also has a brain disorder, but MRI also shows brain damage. And the younger one’s MRI shows everything is fine, with a bad fuse. Aminalon helps the older man a lot. Analogue of Russian imported Gammalon.

1 day break), Ginko biloba (a very good drug, proven by doctors in humans, I specifically studied this topic). They also drank glycine, betaserc (if you have dizziness, it helped a lot!!!), aminalon, nootropics, cinnarizine, piracetam. This is what I remembered. The drugs helped, maybe. Mom even lost consciousness for a short time, and there was severe dizziness....

We waited up to 3 years, which I really regret, you need to periodically visit a neurologist, find a good one if they prescribe amino group drugs (amino acids are also called nootropics) pantogam, aminalon, and if they tell you to inject cortexin, for example, do not refuse immediately, amino acids are excellent drugs , cortexin (actovegin) helps the brain, saturates it with oxygen. Of course, at 1.4 years old it’s too early, just for the future, I don’t understand when a child’s developmental delay is confirmed, and the parents say, I won’t give him this crap, give him injections (I said so)! And then they rush around in front of the school, trying to catch up with their peers, so as not to end up in a special school. Advice like everything will work out is not appropriate in...

Mu in the USA and many other countries is classified as a dietary supplement, not a medicine. $15 a jar for a month of use. In Japan, withdrawn from sale due to obvious ineffectiveness.6. Nootropil, Piracetam, Phezam, Aminalon, Phenibut, Pantogam, Picamilon, Instenon, Mildronate, Cinnarizine, Mexidol - placebo drugs.7. Wobenzym. Manufacturers claim that it heals, prolongs life and youth. You should not believe in a fairy tale about a miracle drug that has not been tested in experimental studies just because it is expensive. Drug companies invest hundreds of millions of dollars in testing a drug, even if there is little hope that it can be proven to be effective. We can only guess...

Chil? With pills or talking or combining... I turned to a neuropsychiatrist, he asked me everything, prescribed 1/4 of phenazepam, I took 2 times a day, neuromultivitis, actovegin and aminalon, so what, I took it for a month and again I feel like crap . Before that there were PAs, now not, but internal tension, as he said, is neurosis. If this treatment does not help, then you will need to take antidepressants. I don’t want something... Or I need it, I don’t know anymore. Maybe to someone else...

In many other countries it is considered a dietary supplement, not a medicine. $15 a jar for a month of use. In Japan, withdrawn from sale due to apparent ineffectiveness. 6. Nootropil, Piracetam, Phezam, Aminalon, Phenibut, Pantogam, Picamilon, Instenon, Mildronate, Cinnarizine, Mexidol - placebo drugs. 7. Wobenzym. Manufacturers claim that it heals, prolongs life and youth. You should not believe in a fairy tale about a miracle drug that has not been tested in experimental studies just because it is expensive. Drug companies invest hundreds of millions of dollars in testing a drug, even if there is little hope that it can be proven to be effective. All that remains is...

We also worked closely on speech. Now we take aminalon + picamilon, glycine and magnesium B6, and my mother gave it to me after 3 weeks. There must be regular classes with a speech therapist, I was told, and a speech therapy garden is a must. And we didn’t even get into the regular one ((((in general, let’s at least sign him up with a speech therapist, the fact that they don’t talk here is not the norm, no matter how offensive it may sound. Plus...

Mu in the USA and many other countries is classified as a dietary supplement, not a medicine. $15 a jar for a month of use. In Japan, withdrawn from sale due to obvious ineffectiveness.6. Nootropil, Piracetam, Phezam, Aminalon, Phenibut, Pantogam, Picamilon, Instenon, Mildronate, Cinnarizine, Mexidol - placebo drugs.7. Wobenzym. Manufacturers claim that it heals, prolongs life and youth. You should not believe in a fairy tale about a miracle drug that has not been tested in experimental studies just because it is expensive. Drug companies invest hundreds of millions of dollars in testing a drug, even if there is little hope that it can be proven to be effective. We can only guess...

Today I will tell you a little about the historically first nootropic, which was used in clinical practice even before piracetam and has true nootropic properties by all criteria. And also about its subjective effects, interesting immunostimulating features and the possibility of its use in conjunction with other nootropic drugs.

And we will talk about aminalone or simply gamma-aminobutyric acid in tablets.
There was a rather strange opinion that GABA does not penetrate the BBB; on the one hand, there are a lot of studies on this subject, but after receiving personally empirical data, I began to have certain doubts about the methodology of these studies, because: firstly, the subjective effects of taking aminalon were extremely noticeable, and secondly due to the fact that there are quite a lot of studies according to which taking large doses of GABA on the order of 2500-5000 mg induces the release of growth hormone, which is not possible without the penetration of exogenous GABA into the hypothalamus.
Regarding the pharmacological properties of pure GABA. They are twofold. In small doses of 250-500 mg at a time, it rather causes mild stimulation, which is clearly related to the fact that the brain very readily immediately eats this exogenous GABA and uses it for energy needs; there is a biochemical feature of the brain called the GABA shunt, which is poorly represented in other organs and tissues. Namely, the ability to use GABA for purely energy purposes by first deaminating GABA through GABA transaminase to succinic semialdehyde, followed by dehydrogenation of succinic semialdehyde to succinic acid (which, by the way, can also be used as a mild metabolic stimulant)

And in doses of 1500 mg and above, about 30 minutes after administration, sourness is felt throughout the entire oral cavity, which is quite unusual, and after about 10 minutes, pronounced central inhibition is felt. For about 15-20 minutes, muscle tone drops slightly, posture becomes difficult to maintain, anxiety disappears, and even the slightest bit of euphoria does not appear, just a slightly relaxed state appears. But I repeat, literally for 15-20 minutes, the effect after that goes away very quickly, only mild stimulation remains. This is precisely due to the fact that the brain instantly metabolizes this same GABA for its energy needs, which is why the appearance of such drugs as phenibut and picamilon is associated, and not with the inability of GABA to penetrate the BBB. GABA is simply consumed extremely quickly by the brain, barely having time to demonstrate any inhibitory effects. A drug such as an anti-anxiety or anticonvulsant or a muscle relaxant (like baclofen) simply cannot be used due to the rate of its metabolism.

But as a neurometabolic stimulant, which will be an excellent addition to almost any nootropic course - yes. When taking nootropics, especially effective ones, associated with increased mental stress, it definitely won’t be superfluous to provide an additional source of energy for the brain.
GABA is also used by bodybuilding enthusiasts as an inducer of growth hormone production in dosages of 2500-5000 mg, who do not have enough money for injections of growth hormone, it is not cheap. True, the data specifically on the induction of growth hormone are controversial; there is evidence that taking GABA leads to the release not of growth hormone, but of immunoreactive growth factor and immunofunctional growth factor, which also belong to trophic factors and the effects of which are similar even to BDNF. Intracellular signaling systems for all growth factors generally overlap greatly, making their effects generally very similar. Actually, growth hormone itself also has a nootropic effect similar to BDNF.
But on the other hand, there is evidence that taking phenibut and baclofen, which are agonists of metabotropic GABA receptors, causes the release of growth hormone, and not immune growth factors, so while the devil will break his leg,
Most likely, GABA causes both proteins to be produced if you add 2+2.

What about the practical use of aminalon in the practice of intellectual health among nootropics? Due to the fact that this is mostly a neurometabolic stimulant, a kind of tasty treat for the brain, this drug will not be superfluous for almost anyone. My dosage is 750 mg 2-3 times a day now. But it is possible to drink it at night in a dosage of 2500 mg to enhance the production of growth hormone and immunoreactive growth factors, which will also have a separate and subsequent significant contribution to the healthy activity of both the brain and the body as a whole.

P.S. Oh yes, aminalon also lowers blood pressure and slightly reduces heart rate. Well, it also reduces high sugar levels, but this is also written in the instructions.

Aminalon is a drug with nootropic and psychostimulating effects.

This drug contains only one active component - gamma-aminobutyric acid (0.25 or 0.5 grams per tablet). Also present are auxiliary substances, such as microcrystalline cellulose, anhydrous colloidal silicon dioxide, magnesium stearate and others.

Gamma-aminobutyric acid stimulates metabolic processes in the brain, helps to neutralize and remove toxic substances, which has a beneficial effect on the functioning of thinking, memory, and accelerates the restoration of speech and motor functions after circulatory disorders in the brain.

In addition, the drug helps lower blood pressure and has a positive effect on the condition of patients with diabetes.

Pharmacokinetics

Aminalon is rapidly absorbed from the digestive tract and reaches its maximum concentration in the blood plasma after approximately 1 hour. The breakdown of the drug occurs in the liver and kidneys, after which it is excreted from the body with urine and exhaled carbon dioxide.

Indications for use

The instructions for the drug Aminalon indicate such indications for application:

• atherosclerosis of the cerebral arteries, accompanied by softening of the brain;
• arterial hypertension;
• consequences of traumatic brain injuries, circulatory disorders in the brain;
• vascular diseases in the brain, especially accompanied by headaches and dizziness;
• impairments of memory, speech, attention due to chronic cerebrovascular insufficiency;
• alcoholic polyneuritis and encephalopathy;
• symptom complex of motion sickness (sea sickness).

For children, Aminalon is prescribed for treatment:

• consequences of birth and traumatic brain injuries;
• decreased mental activity and mental retardation;
• cerebral palsy;
• motion sickness symptom complex.

Contraindications for the use of Aminalon

Aminalon is a fairly safe drug and has virtually no contraindications.

Not assigned This remedy is for patients with hypersensitivity to the active component of the drug. Aminalon is also not recommended for acute renal and liver failure.

Mechanism of action

As noted above, when the active component of Aminalon, gamma-aminobutyric acid (hereinafter referred to as GABA), enters the body, it helps restore metabolic processes in the brain.

This occurs due to the interaction of the active substance with certain brain receptors. As a result, the blood supply to the brain is normalized, the respiratory activity of its tissues increases, and energy processes also become more active.

Toxic substances and harmful products exchanges are displayed faster, the efficiency of glucose utilization increases.

All this leads to restore the normal dynamics of nervous processes, the patient’s memory and thinking improve, and the functions of speech and movement, impaired as a result of disruptions in cerebral circulation, are more quickly restored.

In addition, the active component of the drug stabilizes blood pressure, eliminating such unpleasant symptoms as sleep disturbances, dizziness, and convulsions.

Patients suffering from diabetes notice a decrease in blood sugar levels after using the drug.

Method of administration of the medicine and dosage

Treatment begins with small doses of Aminalon, which gradually increase throughout the course.

The duration of treatment is determined by the doctor taking into account the patient’s condition and the desired effect, and can range from 2 weeks to several months.

If necessary, a repeat course may be prescribed after six months.

Treatment for adults

For the first 3-5 days, the daily dose of the drug is 0.5 grams, after which it increases to 1-2 grams.

Treatment of children

According to reviews, Aminalon is prescribed to children depending on age. Usually Children under 3 years old are recommended to take 1 gram drug per day; children aged 4-6 years – 1.5 grams; over 7 years old – 2 grams.

Aminalon can be used to treat so-called “motion sickness” (motion sickness). In this case, children are prescribed 0.25 grams 2 times a day, and adults – 0.5 grams.

Overdose and consequences

The drug Aminalon is low-toxic, so overdose is possible only when very high doses of the drug (10-20 grams) are used simultaneously.

Signs of overdose manifest themselves in nausea, vomiting, stomach pain, headaches. Also, the patient’s temperature may rise, the general condition becomes lethargic, and the person becomes drowsy.

There is no special treatment for an overdose of Aminalon.

The patient needs to rinse the stomach using activated charcoal and prescribe enveloping agents (starch mucus, diosmectite). Further measures are taken depending on the patient's condition.

Side effect

As a rule, Aminalon is well tolerated by patients. But in some cases, such side effects may occur effects:

• fever, fever;
• gastrointestinal disorders, nausea, vomiting;
• sleep disorders;
• lability of blood pressure.

If, after using the drug, the patient experiences such signs, it is necessary to reduce the dose of Aminalon, after which, usually, the patient’s condition returns to normal.

Precautions and special instructions for use

At the moment, there are no reliable studies of the effects of Aminalon on the body of a pregnant woman and fetus, therefore the drug can only be prescribed by a doctor, provided that the expected beneficial effect for the mother exceeds the potential risk for the child.

The same applies to the use of Aminalon during lactation.

During the treatment period, especially at the initial stage, it is better to refrain from driving a car and doing work that requires increased concentration.

You should avoid drinking alcohol during treatment with Aminalon.

Aminalon, as a rule, is not prescribed to children under 6 years of age.

The drug is available with a doctor's prescription.

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Interaction with other drugs

Aminalon may have negative effects on the body when interacting with other drugs.

This drug should be used with caution simultaneously with anticonvulsants, sedative-hypnotic drugs, as well as benzodiazepine derivatives, since this combination can have a depressant effect on the central nervous system.

When antihypertensive drugs are used during treatment with Aminalon, their effect on the body is enhanced.

In elderly patients, circulatory disorders in the brain and the development of hypotension may occur with simultaneous use of Aminalon with nimodipine, vinpocetine, and nicergoline.

Storage conditions and periods

Aminalon should be stored in a dry, dark place, out of reach of children, at a temperature of 25 ºС. Shelf life – 2-3 years.

Release form

The drug is available in the form of white or gray-yellow coated tablets.

Price of the drug Aminalon

The price of Aminalon, depending on the volume of the active substance and the number of tablets in the package, varies from 110 to 250 rubles.

Reviews from doctors and patients

People's reviews about the drug Aminalon are mostly positive.

Patients taking Aminalon note the positive effect of the drug on memory functioning. Even relatives of fairly elderly people write that Aminalon helped their grandparents maintain a sharp memory for many years.

Aminalon copes well even with significant manifestations of the symptoms of motion sickness complex: severe vomiting and weakness.

It must be said right away that the drug is similar to Phenibut in terms of its principle of action and effects, for this reason we will compare them. However, the main difference is that in picamilon the GABA molecule is attached to Niacin or Nicotinic acid, while in phenibut GABA is combined with a stimulating phenyl group. Therefore, read the article about phenibut, then everything will be even clearer.

So, let's look at the GABA molecule and Nicotinic acid. What is known about them today?
GABA is an inhibitory neurotransmitter; it calms you down, concentrates you, and focuses your attention. It is produced on its own depending on your emotional state, therefore, one step away from jumping out of an airplane with a parachute, it will be produced, perhaps, last.
This neurotransmitter can be obtained “from the outside” in the form of a regular supplement, which can sometimes be very convenient when everyone around you on the plane is shaking in fear, waiting for their turn to jump, and your heart rate has barely risen.

1. Vasodilation, improved blood circulation, decreased blood pressure. Very important and useful effects for learning. The brain floods with blood, like muscles during exercise. Harmful metabolites are washed out of the brain, nutrients, such as glucose or vitamins, pass through more easily, which cannot but please our gray matter, which likes to consume energy in large quantities, especially when you are engaged in intellectual activity.
2. Energy. Vasodilation, in addition to glucose, also leads to better delivery of oxygen to the tissues of the body, and glucose and oxygen are the basis for the creation of ATP, energy. But this is not stimulation! In phenibut there is stimulation, but here, rather like in physics, there is potential energy.

It is also worth saying that Nicotine and Nicotinic acid are different substances. Smoking cigarettes is one way to replace niacin. Nicotine is, in fact, an analogue of Nicotinic acid in terms of its effect on the brain and vasodilation, but it is much more harmful and addictive. And to “relax,” smokers will need to smoke more cigarettes over time.

Let's summarize the work of picamilon: It acts through GABA and Nicotinic acid: GABA slows you down, and Nicotinic Acid or Vitamin B3 dilates blood vessels, participates in the production of ATP and pulls GABA through the BBB.
P.S. Picamilon is water-soluble, so you can turn your work/study colleagues into zombie terminators by mixing the drug into a common water cooler. (This is a joke! Otherwise you never know...)

Picamilon course

The dosage will vary between 80-120 mg/day. Those who simply want to improve their mood and be more attentive can limit themselves to 80-100 mg/day; to combat depression and loss of strength – 120 mg. Take in equal portions throughout the day. Preferably after eating.
Contraindications are increased stomach acidity and, again, kidney problems. Side effects of picamilon: rash, dizziness, irritability.
And another important point: any drugs and supplements based on GABA can cause serious dependence, with increased dosages and long periods of time. If you want to protect yourself once again, then take the lower limit of the indicated dosage, or 80 mg/day.

Effects

Picamilon is indeed similar to phenibut in its effects. Here we have an improvement in mood, nervousness and fear disappear, as all excitement is “muffled”. You become calmer and more relaxed. This helps fight embarrassment and shyness. High dosages can turn you into an insensitive boa constrictor with a good mood.

The main difference from Phenibut is the energy and stimulation. Phenibut calms you down, removes fear and gives you activity, namely a light, unobtrusive desire to act. Picamilon does not stimulate, but adds energy, that is, it does not motivate you like phenibut, but it creates resources for energy, it creates ATP. Effects occur within 1-2 hours.

How to help Pikamilon

Picamilon is interesting to combine with additives that have a neutral or slightly stimulating effect on the psyche: Semax, idebenone, ginkgo biloba, piracetam, l-tyrosine, l-phenylalanyl, l-theanine. It should not be mixed with other GABA-based medications: phenibut, noofen, GABA, etc.

Result:

1. Picamilon is an unusual nootropic with a rather specific effect.
2. Effects: Calmness, fearlessness, energy (without stimulation), concentration and mental clarity. You will know exactly what to do and how to do it, no rush.
3. Course – up to 3 weeks, 80-120 mg/day, divided into 3 doses.
4. Can be taken with any non-stimulant nootropics and without GABA-active supplements.
5. Recommendations as with phenibut. Suitable for working on quality rather than quantity, unless there are time constraints.
Good luck guys! See you soon)

In addition to organic and functional disorders due to diseases, injuries and unhealthy lifestyles, there are many natural factors that negatively affect brain function. Stress, poor sleep, genetics and aging also create a need for drugs that help the brain cope with impaired metabolic capabilities. Among the many nootropic drugs, two similar drugs Piracetam and Picamilon have been available on the domestic pharmacological market for many years. Let's take a closer look at their similarities and differences.

Picamilon and piracetam - what's the difference?

The drugs are available in tablets and ampoules. Piracetam at a dose of 400 and 800 mg in tablets and 20% ampoule solution 5 and 10 ml. Picamilon 20 and 50 mg tablets and 10% ampoule solution 2 ml.

There are contraindications, consult a specialist

Piracetam is a single drug containing one active ingredient with the same name. The main effect of piracetam is nootropic. The drug improves the thinking capabilities of the brain, activates perception, and strengthens the brain’s defenses in the fight against hypoxia. In addition to metabolic effects, it has a direct, albeit not pronounced, effect aimed at improving microcirculation in the affected areas of the brain. Almost completely absorbed in the intestines. An important positive effect of the drug is its ability to accumulate in different parts of the brain. Penetrates the placental barrier and is therefore contraindicated during pregnancy. If breastfeeding, the drug should also be discontinued.

Picamilon is also a single drug. Its main component is nicotinoyl gamma-aminobutyric acid. In addition to the nootropic effect, the substance has the ability to correct blood circulation in the vessels of the brain due to its antihypoxic effect. Improving blood rheology enhances the effect of the drug and, when affecting normal vessels, stimulating brain function. Picamilon is not recommended for severe acute cerebrovascular accident. It is excreted by the kidneys, therefore it is contraindicated in case of renal failure.

30 tab.

If Piracetam and Picamilon are compared in terms of the general nature of their action, then both have a similar nootropic effect. In case of poor tolerability or severe side effects of one of the drugs, the doctor may suggest replacing Picamilon with piracetam or vice versa. However, piracetam in therapeutic doses has a stimulating effect and is best not taken before bedtime. Picamilon, on the contrary, has a milder tranquilizing effect.

So, Picamilon or Piracetam, which is better? The answer to this question lies with the treating specialist. It is a neurological specialist who will help you understand the intricacies of the individual organism and make the right choice, or even prescribe Piracetam and Picamilon together so that the effect of the drugs is potentiated.

Both drugs are produced by Russian pharmaceutical companies. The cost is comparable and relatively low (up to 100 rubles per package). Piracetam will cost about 1.5-2 times less.