Analgin is the most common painkiller in our country. This is explained by the fact that the medicine is cheap and is sold without a doctor's prescription. Many people take algin for any pain, without thinking at all about the possible consequences. But few people can say for sure whether analgin is harmful. The harm from this medication can indeed be considerable.

General characteristics of the drug

Analgin is a non-narcotic analgesic of artificial origin.. The active ingredient is metamizole sodium. This drug has antipyretic, antispasmodic and analgesic effects. Most often the medicine is taken for:

• persistent migraines;
• toothache as first aid before visiting a doctor;
• periodic pain in women;
• colic in the kidneys or intestines;
• neuralgia;
• pain after injury;
• postoperative period;
• decrease in body temperature.

People often start taking analgin without consulting a doctor. At the same time, few people are interested in the instructions for this drug, contraindications and possible side effects. And it’s completely in vain, this painkiller is considered quite strong and, if taken uncontrolled, can cause serious harm to health.

If you have menstrual pain, it is advisable not to get carried away with analgin. It is better to take a no-shpa tablet, which will relieve the spasm.

Contraindications for use

The anesthetic has a number of contraindications that cannot be ignored. These include:

• individual intolerance to the components included in the medicine;
• bronchial asthma, especially in the acute stage;
• chronic liver and kidney diseases;
• blood diseases.

Side effects

We should not forget about the possible side effects that may occur if a person uses pills uncontrollably. The following conditions may develop:

• Allergic skin rashes.
• Quincke's edema.
• Anaphylactic shock.
• Exudative erythema.

Side effects may occur even if the therapeutic dosage is observed if a person has hypersensitivity.

If your health condition worsens during treatment with analgin, stop taking the drug immediately.

What is the danger of analgin

Metamizole sodium can be truly dangerous if taken regularly and unsupervised. Doctors say that You can drink only 2 tablets of analgin per day. In this case, it is advisable to use the drug only as first aid, and then switch to more gentle medications. It is better not to use this pain reliever for the treatment of chronic diseases.

If you take this drug for a long time, the following dangerous conditions may occur:

• The number of leukocytes in the blood decreases.
• The functioning of the cardiovascular system is disrupted.
• The functioning of the nervous system is disrupted.
• Attacks of suffocation are observed.
• Blood pressure decreases.
• Thrombocytopenia is observed.

In addition, immunity steadily decreases, a person becomes seriously ill for a long time.

Analgin can be addictive. This is manifested by the fact that after taking the pill it becomes easier for only an hour, then the pain manifests itself with renewed vigor. So the body requires a new dose of medication.

What happens if you drink a lot of analgin and often

If a person drinks 5-6 tablets of sodium metamizole per day, this will ultimately affect his health. The person will periodically experience nausea, vomiting, shortness of breath, tachycardia and abnormal drowsiness. In severe cases, fainting, seizures, tinnitus and kidney failure may occur..

With a significant overdose of analgin, paralysis of the muscles of the respiratory organs can develop, which will lead to suffocation.

Do not forget that analgin has a very bad effect on the kidneys. Thus, according to statistics, about 10% of patients with renal failure acquired this disease due to long-term use of an analgesic.

Leukopenia

Analgin can lead to the development of a life-threatening disease such as leukopenia. In this case, the production of leukocytes, which protect a person from inflammatory processes, decreases. A particular health hazard is posed by the combination of two medications - analgin and amidopyrine, which ten years ago emergency doctors injected unfortunate patients with high fever. These two medications together almost completely kill white blood cells.

The lethal dose of analgin for humans is 15-20 grams.

The benefits and harms of analgin are almost equivalent, and they depend only on the person who takes this medication. If you take the medicine as prescribed by your doctor and take into account contraindications, it will not cause harm to your health.

Analgin is one of the most common and popular drugs. It belongs to the clinical and pharmacological group of pyrazolones - drugs with analgesic and antipyretic properties.

Active component and release forms

The active component of the drug is metamizole sodium. Additional ingredients in the manufacture of tablet forms include sodium lauryl sulfate, potato starch, calcium stearate and talc.

This drug is supplied in the form of oral administration (500 mg tablets), as well as in the form of a 25% and 50% solution for parenteral administration in ampoules of 1 and 2 ml.

Properties and pharmacokinetics

Analgin is able to reduce the intensity of pain and lower body temperature during a febrile reaction (due to increased heat transfer). It has an anti-inflammatory effect due to the inhibition of COX and prostaglandins.

After entering the gastrointestinal tract, the active substance is absorbed quickly and almost completely. The effect develops ½-1 hour after consuming the tablets, and on average 30 minutes after injection. Hydrolysis of metamizole sodium occurs in the intestinal wall, and the metabolites undergo biotransformation in the liver. The level of their conjugation with serum proteins reaches 60%. Metabolic products leave the body with urine.

When should you take Analgin?

Indications for the use of Analgin are:

Analgin: contraindications

Analgin is not prescribed if the patient has individual hypersensitivity to metamizole sodium, additional substances included in the drug or pyrazolone derivatives.

Other contraindications include:

• pregnancy I and III trimesters;
• children's age (under 10 years);
• intolerance to NSAIDs;
• "aspirin asthma";
• acute pain in the abdominal area (until the cause is established);
• pathologies of the hematopoietic system;
• bone marrow dysfunction (in particular after a course of cytostatics);
• acute intermittent porphyria (with blood pressure<100 мм рт. ст.).

Important:Analgin should be prescribed with extreme caution to persons with chronic alcoholism and kidney pathologies.

It is advisable for patients to take the smallest effective dose, that is, the amount of the drug that reduces pain and reduces fever. The dosage is determined by the intensity of pain and fever, as well as relative contraindications.

The tablets should be swallowed without chewing and washed down with a sufficient amount of clean water. They should be taken after meals.

For adolescents under 14 years of age, a single dose is determined at the rate of 8-16 mg/1 kg of weight (for fever, 10 mg/kg is given). For adolescents over 15 years of age, as well as for adults (weighing more than 53 kg), the permissible single dose is 1000 mg (2 tablets).

The permissible daily dose for adolescents (from 32 to 53 kg) is up to 4 tablets, and for adults – 8 tablets.

For elderly and senile people, the daily volume should be reduced, since their excretion of metabolites is somewhat slower. The same tactics are followed if the patient has reduced functional activity of the kidneys.

Important:Long-term use is unacceptable against the background of liver failure.

The total duration of treatment depends on the nature of the disease and the severity of clinical symptoms. If long-term use is necessary, monitoring of the blood picture is required.

Indications for injection of the solution are intense pain of various origins. Dosage for adults – 1-2 ml 2-3 times a day (but not more than 2 g per day). For children over 10 years of age and adolescents, the dose for parenteral administration is determined at the rate of 0.1-0.2 ml of 50% or 0.2-0.4 ml of 25% solution for every 10 kg of weight.

Side effects of Analgin

Metamizole sodium can cause the following adverse reactions:

• (more often - skin rashes and itching, less often - and);
• changes in the blood (in rare cases, leukopenia, thrombocytopenia and agranulocytosis are noted);
• acute decrease in the functional activity of the kidneys;
• red coloration of urine.

Important:clinical signs of agranulocytosis are hyperthermia, inflammation in the oral cavity and genital area.

If there is any deterioration in the patient's condition, even before obtaining laboratory test data, taking metamizole sodium should be stopped immediately.

Interaction with other drugs

Analgin can enhance the effect of ethyl alcohol, so it does not need to be taken together with pharmaceutical or homemade medicinal tinctures.

When combined with Chlorpromazine, a significant decrease in body temperature is possible.

You cannot take penicillins, radiopaque compounds and colloidal blood substitutes at the same time.

Metamizole sodium tends to reduce the plasma concentration of Cyclosporine.

Analgin increases the therapeutic activity of Indomethacin, glucocorticosteroid hormones and indirect anticoagulants, since it prevents their conjugation with blood proteins.

When taken in parallel, barbiturates reduce the effectiveness of Analgin, while codeine and drugs increase it.

Oral contraceptive pills, Allopurinol and tricyclics can increase the toxicity of metamizole sodium.

Overdose

• a sharp decrease in body temperature;
• (significant drop in blood pressure);
• general weakness;
• cardiopalmus;
• confusion;
• respiratory muscle paralysis;
• development of acute liver and (or) symptoms.

In case of overdose, it is necessary to induce vomiting in the victim and perform gastric lavage using a tube. For binding and accelerated excretion of the active substance, () and salt are indicated. In severe cases, it is necessary to take immediate measures to maintain vital functions. Forced diuresis, hardware blood purification through hemodialysis, and administration of drugs to alkalize the blood are prescribed. The development of seizures is an indication for intravenous injections of fast-acting barbiturates and Diazepam.

For whom is Analgin especially dangerous?

The likelihood of developing severe hypersensitivity reactions is higher in patients with the following pathologies:

• hypersensitivity to NSAIDs (asthmatic or allergic reaction);
• ethanol intolerance;
• intolerance to benzoates (common preservatives).

Give with caution to victims with multiple traumatic tissue injuries. Close monitoring of hemodynamic characteristics is necessary if the patient is diagnosed with acute pathologies of the heart and blood vessels (in particular -) or arterial hypotension. There is a high risk of complications from drug therapy with this drug in people suffering from dehydration.

Important:if an “acute abdomen” is diagnosed, metamizole sodium, as well as other analgesics, should not be given in order to avoid “blurring” the symptoms.

There is no data on the likelihood of the formation of fetal malformations under the influence of Analgin. Due to a lack of information, women preparing to become mothers are strongly advised to refrain from using the drug in the early and late stages. Since metamizole sodium partially blocks the production of prostaglandins, there is a possibility of early closure of the ductus arteriosus in the unborn child.

Analgin's metabolic products can pass into mother's milk, so this medicine should not be taken by women during lactation. As a last resort, you can feed the baby no earlier than 2 days after administration.

banned all over the world, except for our country, it also affects the reproductive system (not in the best way, of course)

Is it true. And it also affects the liver and stomach. It is only good together with diphenhydramine in injections to bring down the temperature. And so in modern medicine they have almost abandoned it.

It’s not true, it has long been proven that it’s not on the heart, but on the liver.

In general, painkillers are one of the most popular medications in the home medicine cabinet, and analgin is the king and god among them. Migraine or teeth, painful menstruation, severe hangover - everything is “extinguished” by inexpensive and familiar analgin. In addition, it is taken as an antipyretic. True, analgin does not eliminate the cause of the ailment, but only muffles the unpleasant sensations, but it is precisely because of these properties that it is in such great demand. Did you know that Russian pharmaceuticals are one of the last bastions of resistance to the World Health Organization (WHO), which is fighting this universal drug.

WHO has long made a strict recommendation regarding analgin: its use should be limited as much as possible. In the USA, Norway, Great Britain, the Netherlands, Sweden, this medicine was excluded from the pharmacopoeia back in the 70s, and in general its consumption was forcibly reduced in 34 countries. Our pharmacologists, of course, know that analgin causes serious side effects. It suppresses the function of the bone marrow, limiting its production of white blood cells - red blood cells that protect the body from infections. In large doses, analgin can lead to death. But many women and girls suffering from painful periods simply revel in analgin during their “critical days,” bringing its consumption to several packs monthly! Analgin is cheaper than safer foreign drugs and can successfully compete with them. The Russian pharmaceutical company ICN alone, according to the newspaper Vremya MN, sells 8 thousand packs of analgin weekly through its network of pharmacies! This, apparently, lies the secret of our stubborn resistance to the alarming directives of WHO experts. True, changes have now been made to the instructions for use of this medicine, but to be frank, who carefully studies the instructions for over-the-counter medicines? The same taste, the same analgin.

yes, because it dilates blood vessels. If you take a large dose, it can lead to bad results

the use of analgin does not affect the functioning of the heart

No, analgin only thins the blood and should be used in the correct dosage and for its intended purpose.

analgin is already banned because it affects not only the heart, it can cause blood cancer

Is it true that the use of analgin affects the functioning of the heart?

Analgin and its “brothers” act directly on the peripheral nervous system. Their task is to suppress pain where it manifests itself. There is another type of analgesics - narcotics, which eliminate pain through the brain. The fact is that the body itself secretes painkillers - opiates. Narcotic analgesics are essentially artificial opiates that are added to natural ones to more effectively suppress unbearable pain - for example, in cancer. But the body senses that opiates are coming in large quantities from the outside, and stops producing its own. Drug dependence occurs. The next dose of opiates did not arrive - withdrawal began. Such narcotic analgesics are known to be sold strictly by prescription. But you can also get used to an over-the-counter painkiller if you do not treat your poor health, but only eliminate the pain symptoms. In principle, there are no harmless drugs; there are none among analgesics. It’s just that some have more side effects, others have fewer.

Analgin is a cheap painkiller, and it is profitable for the pharmaceutical industry to produce expensive painkillers that are no better than analgin, so the production of analgin is prohibited. It is good that Russia did not obey this ban.

The good old killer, or why analgin is banned

Analgin is one of the few drugs that do not need advertising. Since childhood, we have memorized the advice of mothers and grandmothers: “Does your head or stomach hurt?” Women's pain? Pain in the back, leg or arm. “- there is only one recipe: take analgin and everything will go away. The World Health Organization has been trying to eradicate the habit of swallowing the popular drug for five decades. Svidomo found out why.

The drug appeared in 1920. It was synthesized by the German chemist Ludwig Knorr. Half a century later, the triumphant spread of analgin around the world began to be replaced by a wave of alarming reports about dangerous side effects. Some doctors even claimed a mortality rate of 7% of use. In 1970, WHO recommended that all countries abandon analgin.

Now you can’t buy it in pharmacies in dozens of developed countries, for example: the USA, Canada, Britain, Germany, Norway, Denmark, Sweden, Australia and Japan. “Too high a health risk.” This is how the American Food and Drug Administration justified its ban on analgin back in 1977. Since then, evidence that the risk is “too high” has only grown.

In our country it is difficult to find a person who is not familiar with analgin. But it is even more difficult to find someone who would read the instructions before swallowing these pills. If you decide to do this, you will learn about three contraindications: if you are under 12; if you are allergic to any part of the pill; if you are pregnant. Even if this is not about you, further in the instructions there is a long list of side effects. From tinnitus to Lyell's syndrome. Symptoms of this syndrome are a sudden jump in temperature and a rash of painful blisters on the body that will come off along with the skin. But the biggest threat is getting a blood disease, agranulocytosis. This is when the number of leukocytes and granulocytes (white blood cells) in the blood, which protect our body from external and internal enemies, decreases. As a result, a person’s immunity decreases and he becomes susceptible to all kinds of infections, bacteria and fungi. It is because of this that the authoritative British textbook “Clinical Pharmacy” calls analgin “notorious.”

The British have confirmed this stigma with numerous studies. Interestingly, one of them was partially financed by the manufacturer of analgin, the Hoechst company. The study was conducted by the Department of Pharmacological Epidemiology at Boston University. Doctors analyzed patients from different hospitals in different countries: Barcelona, ​​Berlin, Milan, Budapest, Sofia and Stockholm. Data from half of the cities studied showed: the chance of getting a blood disease among those who use analgin is 23 times greater!

What does the Ministry of Health of Ukraine think about all this? His recommendations for doctors suggest prescribing analgin without special reservations. “Headache, toothache, neuralgia, radiculitis, myositis, pain during menstruation,” advises

Ministry of Health for the 41st year after the WHO call to ban analgin.

What to do if you have pain

Svidomo will not take upon itself the sin of advertising a specific drug. Universal advice for any pain: go to the doctor. Analgin, like many other drugs, is a symptomatic medicine that simply does not allow the pain signal to reach the brain.

In Ukraine, where most pills can be bought without a prescription, which means there is even less incentive to go to the doctor, the situation could be much worse. So you start correcting it from yourself.

Comments from our experts

Tatyana Golofeeva, pharmacist:

Even twenty years ago (), when I studied at the Leningrad Pharmaceutical School, at lectures teachers told us that analgin has a negative effect on the heart. Popularly, this action is called “settling” the heart. This information was etched into my memory from my student days. And I want to note that I don’t have analgin in my medicine cabinet at home. There are many other medications that relieve pain. Nowadays, it is not difficult to find an alternative to the same analgin. For children, the pharmacy where I work has ampouled (that is, in ampoules) analgin and in suppositories. Analgin tablets are not prescribed to children. In pediatrics, the basis of all medications is paracetamol.

I urge all people to be sure to read the instructions for any medication. Namely, information about side effects. After all, if you read about the side effects of analgin, then a whole paragraph is devoted to this. And people often don’t even read the instructions, let alone information about side effects. In any case, you should never prescribe medicine for yourself (and our people like to treat themselves, thinking that they know everything). Only a doctor has the right to prescribe this or that drug. By contacting a doctor, most importantly, you will protect yourself and protect yourself from all sorts of side effects of analgin. And in conclusion, I want to say that it is not recommended to abuse any medicine, and especially analgin.

After reading the material of the articles, I got the impression that the author of these lines did not particularly bother himself with researching this problem, he simply took a ready-made publication, slightly “combed it” and presented it to the public under the guise of a “hot topic”. Akin to fast food - bright packaging, easy to prepare, easy to swallow, easy to digest, but has negative consequences.

I'll try to explain my point of view. If you take a pharmaceutical reference book for doctors, then when describing any medicine, the mechanism of action, recommended courses and doses, area of ​​application (indications), as well as contraindications and possible side effects are indicated. I would like to clarify right away: any medical student studies pharmacology for a year, after which he takes an exam. However, there is also such a discipline - clinical pharmacology, which is a logical continuation of the previous (general) pharmacology. Let's add here special literature on the interaction of drugs and their rational use - any competent doctor always uses such information. However, the final ability to competently use medications is developed at clinical departments under the guidance of practicing specialists.

This raises the question: why are the available drugs used so ineptly? There are several reasons for this: the level of training of specialists, the “information hunger” of practicing doctors, the “venality” of many scientific publications that publish information to please pharmaceutical manufacturers, the “squeezing” of doctors by strict orders and recommendations of higher “scientific” officials, and so on.

Just don’t accuse me of being biased towards pharmacists - I deeply respect their hard work. The problem is different: knowing the “madhouse” going on in clinics, out of compassion they make concessions to customers.

Let's return to the ill-fated analgin. “Scientific” men “exposed” his terrible nature. However, then let's ban aspirin with its tendency to cause stomach ulcers and... development of a dangerous condition - “aspirin” asthma. By the way, 20 years ago, all annotations for this drug indicated a side effect - thrombocytopenia. Nowadays this phenomenon is used by many doctors and is popularly called “blood thinning.”

If a person’s back hurts or their joints are inflamed, we inject and swallow nimids, diclacs, nurofens and other related drugs. At the same time, few people think about the ability of these drugs not only to cause ulcerative processes in the gastrointestinal tract, but also about their aggressive relationship to the liver and kidneys.

They advertise “Gepabene” on TV - you can listen to the nightingales sing! But at the same time they modestly keep silent about the fact that long-term and uncontrolled use of this drug leads to the opposite effect (hepatotoxicity). Such examples can be continued ad infinitum...

Any pharmaceutical drug can have a damaging effect. The point is not that they should be banned indiscriminately, but that they should be able to be used wisely. We won’t ban a kitchen knife just because someone cut their fingers with it.

And one last thing. The articles introduced the concept of “Lyell's syndrome”. Just horror and horror. Only when applying this concept, the author of the articles did not deign to inquire about its essence. So, Lyell's syndrome is a toxic-allergic necroepidermolysis, which develops with the use of sulfonamides, penicillins, tetracyclines, barbiturates, contraceptives, etc.

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Danger and harm of analgin - myth or reality?

The most popular medicine that citizens of our country use to relieve pain is analgin. It is taken absolutely uncontrollably, without a doctor’s prescription, and the availability of analgin is often abused, without thinking about the side effects and harm to the body. Analgin has been completely withdrawn from trade in a number of countries, namely: Italy, Denmark, USA, Great Britain. But nevertheless, in some countries of South America, Asia and Europe (including Ukraine) it continues to be used everywhere.

Analgin (metamizole sodium) is used as a powerful analgesic, antipyretic and antispasmodic agent. It is prescribed for acute pain of medium and low intensity of various origins (biliary, intestinal and renal colic, neuralgia, myalgia, trauma, swelling, headache or toothache, dysmenorrhea, radiculitis, febrile syndrome in inflammatory diseases, etc.)

Side effects from taking analgin are often underestimated, but they exist and are quite serious. Complications include allergic reactions (especially from the urinary and nervous systems), hematological, cardiovascular complications, and local disorders.

When self-medicating, you must carefully read the instructions (insert leaflet) of the drug. The adverse reactions indicated in it are expected, that is, they most likely will not occur if the patient first consults with the attending physician, who will assess whether there is any risk associated with taking the drug.

Metamizole (analgin) for many decades was an emergency drug in our country, and not a means for the treatment of chronic diseases. That's how it should remain.

One of the most serious side effects of analgin, which seriously worries doctors, is associated with a serious blood disease - leukopenia. Long-term use of analgin can negatively affect the number of leukocytes. But the reasons for this phenomenon include reduced immunity and poor ecological environment in the patient’s place of residence. The occurrence of leukopenia is also possible with long-term use of any non-steroidal anti-inflammatory antipyretic drug, such as aspirin or paracetamol. Only you won’t find such a warning in the annotations to the latter!

Recently, a fairly aggressive campaign has been launched against analgin on the Internet. Many domestic experts consider it custom-made and beneficial, first of all, to large manufacturers of new expensive drugs.

In the 60s of the last century, medical circles were shocked by a report from the United States: women taking the drug thalidamide for a number of years led to the birth of several thousand malformed children. WHO has tightened control measures. If even isolated, but serious cases of adverse reactions were recorded in one or two countries, the drug was immediately banned. Nowadays, sufficiently proven drugs are entering the global pharmaceutical market. For example, in the USA, up to one and a half billion dollars are spent annually on the program for their study. However, there is one significant “but”: according to the criteria of the same WHO, the maximum positive and negative effects of a medical drug are revealed from the moment of its mass production and use throughout the years!

The legislation on pharmacotherapy in our country requires tightening. Advertising in the media alone is worth it! Actors in the role of doctors call for taking certain “harmless” medications - isn’t this absurd? In no other European country will you see advertisements for medications on a bus or tram. And here we do it in violation of international and domestic regulations. There have not been, are not, and are not expected to have safe drugs in the foreseeable future.

This entry was posted on Monday, February 7, 2011 at 16:18 in the category Medicine. Instructions for use. You can subscribe to new comments on this article: RSS 2.0. You can leave your comment, or trackback from your site.

4 comments to “Danger and harm of analgin - myth or reality?”

1. MED.K writes:

I’ve been saying for a long time that it’s time to put an end to this unbridled (and pharmacologist-funded) bacchanalia. In pharmacies, citizens in white coats (who have primary medical education) freely make the most complex diagnoses, without bothering themselves much... I wonder - why do medical institutes maintain medical faculties? If making a diagnosis is so simple.

What is this “allergic reaction from the urinary and nervous systems”? The author may have confused the concept of allergy as a pathological reaction to a foreign agent and the consequences of this reaction on body systems (primarily the cardiovascular in severe cases).

Otherwise, the article is necessary and useful, in my opinion.

The article is stupid, useless and illiterate. For the author, “pain reliever” is obviously derived from the words “bal” and “balit”. For everyone else, in a normal situation, analgin is a pain reliever.

Until when will doctors prescribe medications to a patient without a preliminary examination, but only based on his story about his state of health? Moreover, the list of medications is not on a prescription form, but on a random piece of paper with advertising that has nothing to do with the patient.

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What harm is there from analgin if analgin is banned in the West due to harm?

Is analgin harmful?

We traditionally use analgin treatment very widely.

Analgin is considered almost a panacea for all diseases.

But abroad, analgin is not among the widely used drugs, and there is even an opinion that analgin is harmful to human health.

So is there any harm from analgin and what kind of harm?

There are no harmless drugs, and I believe that the harm of analgin is not at all a myth, as many people think. This is not a panacea, and all over the world, including in developed European countries, it was banned for a reason.

Russian pharmaceuticals are one of the last to fight for analgin against the World Health Organization, since it is cheap and effective. It has a large number of side effects; of course, it does not eliminate the cause of pain and is addictive. Many, because of such drugs, bring their disease to the chronic stage, because They do not treat, but simply “drown out” the symptoms.

Many of my friends drink several packs of analgin during menstruation. This is not normal, I think.

Any drug, of course, has its side effects. Why such attacks on analgin. Analgin, like paracetamol, as well as aspirin, is an NSAID, a non-steroidal anti-inflammatory drug. And its side effects are the same as those of aspirin and paracetamol. Only unlike them, it has more breadth of therapeutic action, that is, it is more difficult to overdose. And such drugs as baralgin, spasmalgon, maxigam, revalgin, spasmalin, baralgetas, baral. One of the components of which is metamizole sodium (the international generic name for analgin). Half of these drugs are foreign-made. So where they fight it, only in the USA, for the sake of their paracetamol. But paracetamol is toxic and affects the liver. 4 grams of paracetamol and you have cirrhosis. We have been using Analgin for 90 years, in our country it is used in tons, and if it had such side effects, our whole country would have died out.

Of course, it is not a panacea for all diseases. But sometimes there is no drug better than it. As an antispasmodic, it is one of the most effective. As an antipyretic, and much more. Now, of course, it has already been supplanted; radicular pain is better treated with diclofenac. It is supposedly better to reduce the temperature with nurafen (by the way, our ibuprofen) But as an ambulance it cannot be replaced for hepatic and renal colic. Somehow they stopped buying it from us, our bosses, having read articles about it, thought that there was no need to buy it. We had problems, it turns out that it is a good antipyretic. We tried everything and nurofen, and paracetamol, diclofenac. And the patient’s temperature is 40, nothing helps. We went to the departments and gave 2 am. It’s good to use in moderation and correctly. You don’t need to drink tons of it, but use it strictly according to indications.

if you drank analgin, you probably noticed that the urine is colored, becomes reddish, this is one of the harmful properties of analgin - a negative effect on the kidneys, when taking this drug, various degrees of an allergic reaction are possible, up to Quincke's edema, but the most dangerous is that that analgin affects hematopoiesis, changing the structure of the blood in a bad way.

When used frequently, Analgin is harmful and can even cause severe changes in the blood count. But it should be remembered that other medications are not harmless. For example, paracetamol at a small dosage can become extremely dangerous for the liver and kidneys. Aspirin is contraindicated in childhood.

Analgesics and antipyretics should be taken strictly according to indications and for a short amount of time - one day, maximum three days. If symptoms do not go away, be sure to see a doctor.

It should be remembered that when you have a cold, you should only bring down a sufficiently high temperature. You should not take analgin or paracetamol with a slight increase in temperature.

I was convinced from my own experience that analgin is very harmful to the heart and kidneys, it takes a very long time to be eliminated from the body in the urine, and has no beneficial effect on the blood, including during menstruation. for example, I know real cases when some ladies, going on an intimate date, knowing in advance that a surprise may happen in pastels, i.e. That is, if you go on your period at the most crucial moment for both partners, if you take analgin the day before, or a couple of days before, then your period will not come on time, but there will be a delay of 3-4 days. Out of ignorance, I used to take analgin for headaches and other pains, until one day, without waiting for my period on the due day, I ran to the doctor, thinking that I was pregnant, but it turned out, no, I just delayed my menstruation with analgin, which I never do anymore. I declare with complete confidence that ANALGIN is very HARMFUL, especially for the female body.

Doctors have come to the conclusion that analgin, so familiar to us since childhood, is harmful to health, although small doses of this medicine are still considered not dangerous. The main negative effect of analgin on the body is that it poisons the liver. In addition, with regular use of analgin, a person develops addiction, or even worse - dependence. This is noticeable by the fact that with a headache, after taking the pill, the pain disappears for several hours, but then appears again, requiring another dose of analgin. Scientists have also discovered that analgin in combination with amidopyrine) has a very bad effect on the blood, killing leukocytes in it.

I don’t know if it’s true, but analgin delays the onset of menstruation by 3-4 days if taken for a headache or some other pain, a couple of days before, or on the eve of menstruation. verified by personal experience. Some ladies, if they are going on an intimate date, know what can happen, i.e. unexpectedly for the partner, she has red days, a day or two before them they specially take analgin, thereby delaying the natural process for several days! as well as analgin does not have a beneficial effect on the heart and kidneys, and is excreted from the body in the urine for a long time. When I learned about such side effects, I threw away the entire drug, even though it was not yet expired.

There may be harm from analgin, but one tablet of analgin brings down the temperature to 39.8 in half an hour. But paracetamol up to four tablets does not cope with this. Doctors believe that analgin should be taken no more than three tablets a day and no more than three days at all. It has a negative effect on the kidneys and can lead to allergic dermatitis. If you take analgin for a very long time, you may experience suffocation and a decrease in blood pressure. All medications should be taken in moderation and as recommended by doctors.

In many countries around the world, analgin is generally prohibited for sale as a pure substance.

And it’s not for nothing that such a restriction was introduced. Analgin is harmful to the body.

1.Severely affects the kidneys. 10% of people attending hemodialysis procedures have abused analgin in the past.

2. This drug significantly inhibits the hematopoietic function of the bone marrow. Immunity is greatly reduced, because the bone marrow produces our body's defense - leukocytes.

And other analgesics are not a “gift” for health. They only drown out the pain, leaving the problem of its occurrence unresolved.

Numerous studies have proven that excessive use of analgin leads to kidney failure. Analgin is also capable of suppressing bone marrow tissue in large quantities, thus limiting the production of leukocytes, which leads to poor resistance of the body to infections.

And analgin can also be addictive. And your head will hurt for no reason, requiring you to take analgin again.

Analgin, like every medicine, has a whole list of side effects, where without them. For analgin, this is an allergic reaction, impaired renal function, red coloration of urine, disruption of the functioning of the hematopoietic organs, and decreased blood pressure.

By the way, this applies not only to analgin, but to all medications based on metamizole sodium. For example, baralgin, optalgin and others.

Analgesics cause blood cancer. The oldest and most popular remedy (banned in Europe and replaced by ibuprofen).

It should be noted that many painkillers are complex, so they can simultaneously affect several aspects. I prefer tempalgin based on analgin.

When taking analgin, leukopenia is possible. This is a blood disease associated with a lack of white blood cells. Other side effects are also possible: allergic reactions, hematological, cardiovascular complications, local disorders.

and I’ve heard for a long time that analgin affects the heart, and since I very rarely take pills, if necessary, for general pain I still use baralgin, and if I have a headache, then citromon

Is there any harm from analgin?

Analgin is the most common painkiller in our country. This is explained by the fact that the medicine is cheap and is sold without a doctor's prescription. Many people take algin for any pain, without thinking at all about the possible consequences. But few people can say for sure whether analgin is harmful. The harm from this medication can indeed be considerable.

General characteristics of the drug

Analgin is a non-narcotic analgesic of artificial origin. The active ingredient is metamizole sodium. This drug has antipyretic, antispasmodic and analgesic effects. Most often the medicine is taken for:

• persistent migraines;
• toothache as first aid before visiting a doctor;
• periodic pain in women;
• colic in the kidneys or intestines;
• neuralgia;
• pain after injury;
• postoperative period;
• decrease in body temperature.

People often start taking analgin without consulting a doctor. At the same time, few people are interested in the instructions for this drug, contraindications and possible side effects. And it’s completely in vain, this painkiller is considered quite strong and, if taken uncontrolled, can cause serious harm to health.

If you have menstrual pain, it is advisable not to get carried away with analgin. It is better to take a no-shpa tablet, which will relieve the spasm.

Contraindications for use

The anesthetic has a number of contraindications that cannot be ignored. These include:

• individual intolerance to the components included in the medicine;
• bronchial asthma, especially in the acute stage;
• chronic liver and kidney diseases;
• blood diseases.

Side effects

We should not forget about the possible side effects that may occur if a person uses pills uncontrollably. The following conditions may develop:

• Allergic skin rashes.
• Quincke's edema.
• Anaphylactic shock.
• Exudative erythema.

Side effects may occur even if the therapeutic dosage is observed if a person is hypersensitive.

If your health condition worsens during treatment with analgin, stop taking the drug immediately.

What is the danger of analgin

Metamizole sodium can be truly dangerous if taken regularly and unsupervised. Doctors say that you can only drink 2 analgin tablets a day. In this case, it is advisable to use the drug only as first aid, and then switch to more gentle medications. It is better not to use this pain reliever for the treatment of chronic diseases.

If you take this drug for a long time, the following dangerous conditions may occur:

• The number of leukocytes in the blood decreases.
• The functioning of the cardiovascular system is disrupted.
• The functioning of the nervous system is disrupted.
• Attacks of suffocation are observed.
• Blood pressure decreases.
• Thrombocytopenia is observed.

In addition, immunity steadily decreases, a person becomes seriously ill for a long time.

Analgin can be addictive. This is manifested by the fact that after taking the pill it becomes easier for only an hour, then the pain manifests itself with renewed vigor. So the body requires a new dose of medication.

What happens if you drink a lot of analgin and often

If a person drinks 5-6 tablets of sodium metamizole per day, this will ultimately affect his health. The person will periodically experience nausea, vomiting, shortness of breath, tachycardia and abnormal drowsiness. In severe cases, fainting, seizures, tinnitus and kidney failure may occur.

With a significant overdose of analgin, paralysis of the muscles of the respiratory organs can develop, which will lead to suffocation.

Do not forget that analgin has a very bad effect on the kidneys. Thus, according to statistics, about 10% of patients with renal failure acquired this disease due to long-term use of an analgesic.

Leukopenia

Analgin can lead to the development of a life-threatening disease such as leukopenia. In this case, the production of leukocytes, which protect a person from inflammatory processes, decreases. A particular health hazard is posed by the combination of two medications - analgin and amidopyrine, which ten years ago emergency doctors injected unfortunate patients with high fever. These two medications together almost completely kill white blood cells.

The lethal dose of analgin for humans is grams.

The benefits and harms of analgin are almost equivalent, and they depend only on the person who takes this medication. If you take the medicine as prescribed by your doctor and take into account contraindications, it will not cause harm to your health.

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For medical assistance, we strongly recommend that you consult a doctor.

Is Analgin harmful? Is Analgin really banned all over the world? What is an allergy to Analgin? This is a common painkiller that raises more questions about its use than other medications. The drug, which is highly effective and has a minimal retail price, is, however, not as simple as it seems. This is a serious medication that, if used incorrectly, can cause serious harm to health.

This drug is a derivative of pyrazolone, it has a number of important properties:

• antipyretic;
• pain reliever;
• anti-inflammatory (low level).

The mechanism of action of the drug is due to the ability of its active substance to block the production of cyclooxygenase, the enzyme responsible for the processing of arachidonic acid into prostaglandins (the main participants in inflammatory processes that provoke an increase in body temperature and increased pain). Metamizole does not allow pain impulses to exceed the sensitivity threshold of the pain center and reduces the brain's reactions to negative sensations provoked by various types of irritants.

This medication is a common painkiller, which is achieved by inhibiting the function of prostaglandins. It has the ability to bring elevated thermometer readings back to normal, which is made possible by reducing the production of special chemicals that affect the body’s heat exchange processes. The medication has the property of relieving spasms by affecting the smooth muscles of muscle organs and relaxing them.

Analgin, despite the fact that its use can provoke dangerous consequences, is a non-narcotic analgesic substance. This purpose makes it possible to use it as an antispasmodic, antipyretic and analgesic drug.

The medicine is used for the following indications:

• persistent migraines;
• toothache (for a short period, until you seek medical help);
• menstrual pain;
• neuralgia;
• renal, intestinal colic;
• painful sensations accompanying injuries, burns, cuts, postoperative recovery;
• elevated body temperature during ARVI.

Despite the fact that Analgin is banned in a number of European countries, many people purchase it without a doctor's recommendation. Few people study the indications and contraindications for its use and are interested in possible side effects. However, this medicine, despite its apparent safety, can seriously harm human health.

It is worth remembering that there is a high probability of developing an allergy to Analgin. This painkiller, the main active ingredient of which is metamizole sodium, when taken very often, without following medical recommendations, can provoke the development of serious allergic reactions. The medication very quickly goes through all stages of absorption into the systemic bloodstream, so reactions can develop almost instantly. Allergy to Analgin symptoms are quite negative, requiring timely relief.

This situation develops especially often when a person takes the drug on a long-term basis, whereas experts consider it a means of providing quick help (for temporary relief of negative symptoms, followed by contacting a medical facility).

It is worth remembering that this medication is not approved for use by all patients. The instructions contain a list of conditions when its use is prohibited.

Analgin has the following contraindications for use:

• personal intolerance or severe sensitivity to any components contained in the drug;
• liver, kidney failure;
• dysfunction of cytostatics, inhibition of hematopoietic processes, including that observed during the use of cytostatic substances;
• leukopenia;
• hemolytic anemia of hereditary type, other types of this pathology;
• rheumatic attacks;
• dysmenorrhea;
• children under 10 years of age;
• pregnancy (especially the first and last trimesters);
• intolerance to nonsteroidal drugs, bronchial asthma and acute reactions to aspirin.

How does Analgin harm human health? This drug can provoke the occurrence of such side effects:

• headache;
• dizziness;
• the appearance of a skin rash accompanied by severe itching);
• decreased blood pressure;
• feverish condition;
• the risk of developing agranulocytosis (this risk especially increases if the medicine is taken without interruption for a week or more);
• leukopenia;
• hepatitis;
• anemia;
• dysfunction of the liver, kidneys;
• increased daily urine output;
• the appearance of acute renal failure (which can negatively affect the heart).

The period of therapy using this pharmaceutical requires attention to some important points:

1. The drug is prohibited for use for the purpose of relieving acute pain in the epigastric region. This can lead to the erasure of dangerous symptoms and will not allow the person to receive medical assistance in a timely manner. If such symptoms develop, you can take the drug only after receiving the results of a blood test and examination by a specialist.
2. The period of long-term therapy requires mandatory monitoring of the leukocyte blood count in order to prevent possible inhibition of hematopoietic functions.
3. Elderly patients suffering from kidney and liver diseases should take reduced doses of medications, because the functions of its removal from the body may be slowed down.
4. People suffering from pathologies of the cardiovascular system must constantly monitor their heart rate, blood pressure, and breathing rate.
5. Patients suffering from alcohol dependence, intolerance to certain medications, frequent allergic reactions, and bronchial asthma have a high risk of developing anaphylactic shock, so they should take the pills with extreme caution and only after the permission of the attending physician.
6. During therapy with this drug, the usual color of urine may change to reddish, which does not pose any health hazard, but is a sign of metabolites being removed from the body.
7. The use of the drug by pregnant women can seriously harm gestation and disrupt the normal development of organs and systems of the fetus. Its use during this period is possible only at the discretion of the doctor, after carefully weighing the benefits to the mother and the risks to the fetus.
8. Long-term use of the drug can lead to a strong myelotoxic effect and is therefore not recommended.

How can Analgin harm a person? Long-term use of pills can provoke the following problems:

• decrease in the number of leukocytes in the blood;
• disorders of the cardiovascular system;
• problems with the functioning of the central nervous system;
• the occurrence of asthma attacks;
• decreased blood pressure;
• development of thrombocytopenia;
• a decrease in the functionality of the immune system, which is why a person begins to get sick for a long time and often.

Analgin can provoke the development of addiction; this can manifest itself in the fact that after each pill taken, he feels better for only a short time, after which there is a need to take a new dose of the drug.

Every person should remember that Analgin can be sold not only in its pure form. The active ingredient of this medicine is included in other drugs. For example, Baralgina, Spazmalgina, Tempalgina, Pentalgina. Therefore, their prolonged and uncontrolled use also needs to be guarded against.

Why is this drug banned in some countries?

An allergy to Analgin, the many side effects that it provokes, all this creates the preconditions for a gradual ban on this medication. Some European countries have not sold this drug in their pharmacies for several years.

In our country, this drug is sold, as well as others containing metamizole sodium, Baralgin and Tempalgin. Most people do not know that Analgin is prohibited, and even if they do know, they do not pay attention to its presence in other complex drugs. This creates a serious danger to their health, because, unaware of the presence of metamizole sodium in the drug, they can take the medicine more often than allowed (thereby causing serious harm to their own body, because the harm of Analgin has been proven).

Is it possible to drink analgin

Is it possible to get poisoned with Analgin? This situation may well happen, just like with any other drug. Analgin poisoning becomes a reality when a person takes the drug on a long-term basis, without following the instructions.

A dose that is fatal to humans is considered to be from 15 to 20 grams of the drug.

The drug, when used for urgent relief of pain, is taken once and, as a rule, does not cause serious harm to the body. If a person takes these pills day after day, for example, to get rid of the pain syndrome accompanying a sprain or fracture of a limb, then the toxic effect will increase, which will lead to the development of adverse reactions.

You can take this medicine only to obtain a short-term effect; it is not used for long-term therapy.

If a person takes no more than 1-2 tablets per dose, he can repeat this no more than three times a day. Moreover, such therapy lasts no more than three days; danger can be avoided.

Otherwise, there is a high probability of developing a dangerous disease - leukopenia. It is associated with a decrease in the production of leukocytes, substances necessary to protect a person from the development of inflammatory processes and infectious diseases. The combination of metamizole sodium and amidopyrine is considered especially dangerous (this combination was actively used several years ago to reduce elevated body temperature). This proximity leads to the complete death of leukocytes, which is extremely dangerous for humans.

As you can see, the medicine has both benefits and harm. Only the patient who decides which drug he will take to relieve pain is responsible for his own health. Taking pharmaceuticals as prescribed by a specialist, in strict accordance with the instructions, brings minimal health risks.

You can always replace Analgin with other, safer drugs. For example, use medications containing paracetamol and ibuprofen, which perfectly reduce elevated body temperature and relieve pain. If you take them according to the attached instructions, then they will practically not cause harm to the body.