Ginkgo biloba 120 is a biologically active preparation of plant origin. The absence of chemically synthesized compounds in it makes it relatively safe. Provided that the medicine is used according to the attached instructions, it will not cause side effects.

Ginkgo biloba L.

ATX

Code - N06DX02. Refers to angioprotective herbal preparations.

Release forms and composition

The composition of the medicine (capsules or tablets) includes processed extract of ginkgo biloba leaves in an amount of 120 mg. Additionally, the capsules contain dyes, fillers in the form of modified starch, povidone and carboxymethyl starch, and cellulose. To give the tablets the appropriate appearance, dyes are used.

1 package can contain 30, 60, 100 capsules or tablets.

pharmachologic effect

A medicine of natural origin regulates metabolic phenomena in the cells and tissues of the body, blood fluidity and microcirculation. The active ingredients included in the composition normalize the processes of cerebral circulation and nutrition, the transport of glucose and oxygen in brain tissues. Ginkgo biloba prevents red blood cells from sticking together and inhibits the activity of platelet activating factor.

Regulates the effect on blood vessels, activates the process of nitric oxide synthesis. Dilates small blood vessels and increases venous tone. In this way, the vessels are filled with blood. It has an anti-edematous effect by reducing vascular permeability. This occurs both at the vascular level and in the peripheral system.

The antithrombotic effect occurs by stabilizing the cell membranes of platelets and red blood cells. The drug reduces the intensity of the formation of prostaglandins and platelet-activating substance in the blood and prevents the formation of blood clots. Ginkgo biloba prevents the appearance of free radicals in cell membranes (i.e., the active substances included in the capsules are antioxidants).

Regulates the processes of release, reabsorption and metabolism of norepinephrine, dopamine and acetylcholine. Improves the ability of these substances to connect with the corresponding receptors. The product has a pronounced antihypoxic effect (prevents oxygen deficiency) in tissues and improves metabolism. Helps increase the processes of glucose and oxygen utilization.

Research shows that using the medication improves eye function. This is especially suitable for patients who wear glasses or contacts.

The medication is not used for weight loss. Not used in dermatology.

Pharmacokinetics

The active compound contains ginkgoflavoglycosides - ginkgolides A and B, bilobalide C, quercetin, organic acids from plant sources, proanthocyanidins, terpenes. Contains microelements, including rare ones - titanium, copper, selenium, manganese. When administered orally, the bioavailability of substances reaches 90%. The highest concentration of components is achieved approximately 2 hours after internal administration. The half-life of the substances of this dietary supplement is on average 4 hours (bilobalide and ginkgolide type A), 10 hours for ginkgolide type B.

In the body, active substances are not exchanged, i.e. they are evacuated by the kidneys and in small quantities with feces in an almost unchanged form. Not metabolized in liver tissue.

Indications for use

Ginkgo biloba is indicated for:

• cognitive deficit in dyscirculatory encephalopathy as a result of stroke, traumatic brain injury;
• impairments of cognitive processes in old age, accompanied by a feeling of fear and anxiety;
• decreased mental acuity;
• sleep disorders of various origins;
• retinopathy caused by diabetes;
• lameness resulting from grade 2 obliterating endarteritis of the legs;
• visual impairment due to vascular dysfunction, including when its acuity decreases;
• hearing impairment, decreased clarity and acuity;
• dizziness and other disturbances in coordination of movements
• Raynaud's disease;
• phlebeurysm;
• dementia;
• depressive state, constant feeling of fear and anxiety;
• various microcirculation disorders;
• diabetes;
• constant ringing in the ears;
• diabetic tissue damage (dangerous conditions that can lead to the development of gangrene in the patient);
• erectile dysfunction (impotence) in men;
• acute or chronic hemorrhoids.

Patients should be advised that the crushed extract from tablets or the contents of capsules is not used in cosmetics, contrary to the statements of some traditional doctors and websites promoting traditional methods of treating skin diseases. The extract is prepared for internal, oral use only. Contact with the skin in its pure form can cause burns and other lesions (due to the presence of quercetin in the extract).

If you add the extract to ready-made cosmetics, they can cause an allergic reaction in a person.

Contraindications

The use of Ginkgo biloba 120 is contraindicated in case of hypersensitivity to the active components. You should not take tablets or capsules in the following cases:

• low blood coagulation;
• ulcerative processes in the stomach and duodenum;
• erosive gastritis;
• the period of waiting for a child and breastfeeding;
• patient age under 12 years;
• heart attack or stroke in the acute stage.

Carefully

Caution should be exercised when treating arterial hypertension. The medicine may cause instability in blood pressure, manifested by sudden increases or decreases. It is necessary to observe the same caution in case of vegetative-vascular dystonia, especially if the patient is prone to hypotension and pressure surges when the weather changes.

How to use?

The medication is taken one capsule 1 or 2 times a day with a main meal. Drink half a glass of clean water (not carbonated). The duration of treatment is approximately 3 months, longer in severe cases.

For cognitive disorders, the dosage regimen is the same, and the duration of administration is 8 weeks. After 3 months, if indicated, a repeat course may be prescribed. The advisability of prescribing a repeat course is determined only by the attending physician.

For ringing in the ears, you need to take the medicine 2 capsules per day for 3 months. For dizziness, occlusive lesions of arterial vessels, Ginkgo biloba 120 is prescribed 1 capsule once a day for 2 months.

For dizziness, it is advisable to take the drug 2 capsules for 8 weeks.

For diabetes

The drug can be used for diabetes mellitus as a prevention and treatment of the underlying disease. Japanese doctors especially recommend the substance to all patients with the third blood group.

In diabetes, the drug significantly reduces the human body's need for insulin. This property of the supplement appears if the patient uses it for at least 1.5 months. In case of diabetes, to correct the level of glycemia and prevent the development of complications, it is necessary to take 2 tablets or capsules 2 times a day with the main meal.

Taking the medicine also helps lower cholesterol levels. To do this, the tablets are taken at the recommended dose for at least 1.5 months. In the future, the therapeutic course can be repeated to consolidate the results obtained. Ginkgo can also be taken in combination with other antidiabetic medications.

Side effects

During treatment, side effects may occur:

• pain in the head, face and back of the head;
• dizziness and loss of coordination of movements;
• symptoms of dyspepsia - nausea, sometimes vomiting, constipation or diarrhea;
• feeling of discomfort in the abdominal cavity;
• reactions associated with hypersensitivity, including urticaria;
• dyspnea;
• skin inflammation, swelling, redness of the skin, itching;
• eczema;
• cerebral hemorrhages, gastric and intestinal bleeding (rare).

If these symptoms appear, you should stop taking the medication and consult a doctor.

Impact on the ability to operate machinery

Caution should be exercised during treatment and when driving a car or operating complex equipment. In some cases, a decrease in concentration and reaction speed is possible.

special instructions

During treatment, it should be taken into account that the first signs of improvement are visible only a month after starting to take the capsules. If during this period there are no changes in health status, then stop taking the medication further and consult a doctor.

If an allergy occurs, stop taking it. Before surgical interventions, therapy with Ginkgo preparations is discontinued to avoid life-threatening bleeding.

The product contains glucose, lactose. If the patient has impaired absorption and metabolism of galactose, deficiency of this enzyme, malabsorption, then it is recommended to stop using it.

If a dose of medication was missed, then the subsequent dose should be taken as indicated in the instructions, i.e. You should not take the missed dose of medicine.

Use during pregnancy and lactation

Prescription for children

Tablets or capsules should not be given to children. Use is permitted in accordance with the current instructions.

Use in old age

Caution should be exercised when using this dietary supplement in patients in this group.

Overdose

With a single use of a large number of Ginkgo preparations, dyspepsia may develop. Sometimes patients experience impaired consciousness and a severe headache.

Interaction with other drugs

When used simultaneously with substances that slow down blood coagulation processes, the risk of dangerous bleeding increases significantly. Such drugs must be used carefully.

Particular observation should be made when using antiepileptic drugs together - Valproate, Phenytoin, etc. Ginkgo can increase the seizure threshold and cause an epileptic attack.

Alcohol compatibility

The product exhibits a vasodilating effect. Alcohol dilates blood vessels, then causes spasm. Drinking alcohol can change the effect of the medicine and cause side effects, so Ginkgo and alcohol are incompatible.

Storage conditions of the drug

Doctors advise storing it in a dark place protected from light.

Best before date

Suitable for 3 years. Further use of the drug is strictly prohibited.

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The huge ginkgo tree with fan-shaped bilobed leaves is one of the most ancient plant species. Its ancestors existed on Earth 300 million years ago. It is not surprising that in Asia, in its homeland, it has always been considered a symbol of hope, longevity, fertility, vitality and invincibility.

Gingko - or actually gingkyo (an error in translation from Japanese) - has almost as many names as there are shades of leaves in nature: silver apricot, temple tree, duck foot tree, elephant ear tree, and so on. The names reflect both the shape and color of the leaves, as well as historical moments: for example, the French paid 40 thalers for the first trees purchased.

Ginkgo biloba: harmony and strength

This ancient tree is the last of its kind - all its relatives went extinct thousands of years ago. Their peculiarity: they shed their leaves in the fall, like deciduous trees, but they have branches without leaves, with a large number of small growths, reminiscent of the needles of coniferous trees. Therefore, ginkgo is more reminiscent of a coniferous tree than a deciduous tree.

Ginkgo is a dioecious plant: in nature there are male and female trees that are pollinated by air currents. Interestingly, ginkgo takes about 20–30 years to become sexually mature. Another feature: ginkgo is extremely insensitive to external irritants - even at a young age, the tree tolerates winter frosts well, and is not afraid of exhaust fumes, road salt, pests, climatic extremes and other influences. It's no wonder it has been around for so long, and each specimen can live up to a hundred years. In Asia, gingko is considered a symbol of harmony and strength. Because of its amazing properties and history, it has been called the “millennium tree.”

Health and beauty thanks to Ginkgo

In Asia, especially in China, the “miracle tree” has long been used to maintain beauty and as a medicinal plant - the seeds or fruits, as well as leaves and bark are eaten for asthma, bronchitis, circulatory disorders, skin diseases, urinary incontinence and anxiety. states. However, they are especially effective for poor concentration and memory disorders.

The preparations use extracts of dried ginkgo leaves, which are obtained in a long process consisting of more than 20 stages. Particularly effective are the flavonoids and terpenoids contained in the leaves, which are found only in this plant in a special form of ginkolides and bilobalides.

Why do plant leaves go through so many stages during processing?

There are two reasons: the valuable ingredients of the leaves are difficult to dissolve in water and therefore cannot be fully used by the body. Moreover, consuming the leaves may even be harmful because natural ginkgo also contains allergy-causing substances. Therefore, gingko preparations add the desired ingredients and remove the unwanted substances.

Ginkgo works! Indeed?

The areas of its application are considered, first of all, to be age-related diseases associated with circulatory disorders and brain performance. Thus, gingko is intended to fight senile dementia by improving or slowing down the process. It is intended to prevent migraines, slow the progression of multiple sclerosis, reduce premenstrual symptoms in women and improve hearing. Gingko can reduce visual restrictions in glaucoma.

Effect of ginkgo extract:

• blood thinning;
• improving blood circulation in small vessels (microcirculation) and, consequently, increasing the content of oxygen and nutrients in the gray cells of the brain;
• interception of harmful aggressive molecules that attack cells;
• protecting nerve cells, preventing their destruction and increasing the effectiveness of their action.

In recent decades, numerous studies have been conducted on the effectiveness of ginkgo. The euphoria surrounding the “miracle drug” was high for many years, after which disappointment set in: several recent clinical studies showed questionable results of previously proven benefits.

Indications for use

There are the following indications for the use of drugs with dinosaur tree extract:

• senile dementia;
• encephalopathy;
• neurosensory disorders;
• memory problems;
• circulatory disorders;
• neuropsychic weakness;
• hair loss.

Additional benefits of drugs with ginkgo biloba include vasoregulatory effects. Medicines with an extract of a relict plant are often prescribed for systemic diseases that occur with serious circulatory disorders. Diabetes mellitus may be an indication for use.

A tincture prepared from ginkgo biloba leaves has irreplaceable beneficial properties.

This drug has an excellent effect on the body and has different indications:

• multiple sclerosis;
• migraine;
• bronchial asthma;
• impotence;
• haemorrhoids;
• deafness.

The tincture is suitable for people of all ages, and after a week of regular use it has a positive effect.

In order to prepare the tincture yourself, you need to take vodka (10 parts) and pour in the leaves of the plant (1 part). Then leave to infuse for 14 days, and after the tincture is ready, strain and pour into another container. You need to take 10-15 drops of the finished product, diluted in 100 g of ordinary still water. It helps strengthen the body, increase immunity and prevent various diseases (cardiovascular pathologies).

Tea with plant extract has excellent healing properties, which helps prevent the development of heart attack, stroke and sharpen mental reactions.

Indications for use of tea with dinosaur tree extract:

• protecting cells from toxic substances;
• improving the functioning of all organs and systems;
• hair strengthening;
• increased blood flow to the brain.

Tea helps to obtain a general strengthening effect, thereby replenishing the lack of vital energy.

Contraindications and side effects

Preparations with ginkgo biloba extract are classified as highly safe. However, taking generic drugs and dietary supplements with insufficiently purified raw materials can cause the development of hemorrhagic complications. They can be caused by a high concentration of ginkgo acids. Even strictly dosed intake of tablets and capsules based on ginkgo biloba can pose a certain threat. In rare cases, you may experience:

• Gastrointestinal disorders;
• Decreased appetite;
• Skin rashes;
• Noise in ears;
• Excessive salivation;
• Vomiting, nausea;
• Dizziness and headache.
• People suffering from epilepsy may experience epileptic seizures while taking ginkgo.

Interaction with other drugs

If, among other components of the drug, there is heptaminol hydrochloride, then a sharp increase in blood pressure, tachyarrhythmia and increased heartbeat are possible.

Concomitant use of ginkgo and efavirenz may result in a decrease in plasma concentrations of the latter.

Like any medicine, ginkgo biloba preparations may have contraindications for use. Therefore, they are not recommended for use without consulting a doctor.

Main contraindications

• Pregnancy (possible hemorrhage in fetal tissue);
• Gastritis and peptic ulcer during exacerbation;
• Age 12-18 years (depending on the drug);
• Acute cerebrovascular accidents;
• Myocardial infarction;
• Tendency to bleeding (cases of severe bleeding have been documented in people who simultaneously took drugs to reduce blood clotting and dietary supplements with ginkgo biloba);
• Individual hypersensitivity to drug components (lactose, dyes, etc.).

Also, ginkgo preparations are not prescribed before operations, because they tend to increase bleeding. You should also not take several dietary supplements containing extract or crushed ginkgo leaves at the same time. Side effects caused by overdose are the most common.

It is dangerous to use ginkgo together with certain medications, such as blood thinners, for this reason you should never take ginkgo preparations without consulting your doctor!

Instructions for use of Ginkgo Biloba

Ginkgo Biloba is available in the form of tablets, powder, liquid, soft gel, but most often the drug is used in capsule form.

The dosage regimen and duration of treatment are determined by the doctor on an individual basis.

When treating chronic long-term conditions, it is possible to use 6 capsules per day.

Ginkgo Biloba should be swallowed whole with plenty of water.

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Nittany Pharmaceuticals inc. AVEN LLC Vertex (JSC) Vertex Joint Stock Company VIS, LLC INAT-PHARMA, LLC Concern Stirol, LLC Naturopharm LLC SVOBODNY 20, CJSC Pharmprodukt, LLC Fitofarm Klenka JSC Evalar CJSC

Country of origin

Russia UNITED STATES

Product group

Other dietary supplements for internal use

a drug that improves cerebral and peripheral blood circulation

Release forms

• 30 capsules in a pack 30 capsules of 370 mg each 40 tablets of 0.2 in a blister 60 tablets in a pack jar 40 caps caps. 80 mg 30 pcs. Tablets 460 mg - 30 pcs per pack Tablets 460 mg - 60 pcs per pack tablets weighing 0.2 g - 40 pcs per pack. tablets weighing 0.45 g - 40 pcs per pack. pack 40 tablets

Description of the dosage form

• capsules tablets tablets weighing 0.5 g Tablets, yellow-green, grassy color Hard gelatin capsules No. 3 (d yellow). The contents of the capsules are a powder or compacted mass of yellowish-brown color with brown and white particles, disintegrating when pressed.

pharmachologic effect

The dietary supplement has antioxidant properties, normalizes cerebral and coronary circulation, eliminates circulatory failure, and restores vascular elasticity. Ginkgo Biloba helps improve brain activity, strengthen memory and, as a result, prolong active life. Carefully selected components have a mild sedative effect, weaken spasm of the coronary arteries against the background of prolonged negative emotions, mental and physical stress, smoothly lower blood pressure, regulate the frequency and strength of heart contractions, and have an anti-sclerotic effect. Description of the components of the Gingko Biloba dietary supplement: Glycine – reduces psycho-emotional stress, increases mental performance, normalizes and activates protective inhibition processes in the central nervous system. Glycine is an essential amino acid that a person must obtain in sufficient quantities from food. * Ginkgo Biloba - normalizes cerebral and coronary circulation, restores memory, hearing, vision, speech and motor functions deteriorated as a result of age-related changes, eliminates circulatory insufficiency (including atherosclerotic and age-related), restores elasticity and strength of blood vessels, prevents thrombosis of cerebral and coronary vessels , improves nutrition of the heart muscle, has antioxidant properties. Ginkgo biloba has a beneficial effect on brain functions: it activates mental activity, improves memory and sleep, relieves dizziness and tinnitus. * Baikal skullcap - dilates blood vessels, slows down the heart rate, eliminates headaches and insomnia, reduces blood pressure, combined with atherosclerosis; prevents the occurrence of seizures, inhibits the functional activity of the nervous system.

Pharmacokinetics

After oral administration of ginkgo extract, the terpene lactones (ginkgolide A, ginkgolide B and bilobalide) have high bioavailability, which is 100% (98%) for ginkgolide A, 93% (79%) for ginkgolide B and 72% for bilobalide. After administration of 80 mg of extract, maximum plasma concentrations are: 15 ng/ml for ginkgolide A, 4 ng/ml for ginkgolide B and approximately 12 ng/ml for bilobalide. The half-life is 3.9 hours (ginkgolide A), 7 hours (ginkgolide B) and 3.2 hours (bilobalide). Plasma protein binding is: 43% for ginkgolide A, 47% for ginkgolide B and 67% for bilobalide.

Special conditions

Improvement in the condition appears 1 month after the start of treatment. If you experience frequent feelings of dizziness and tinnitus, you should consult your doctor. If there is a sudden deterioration or loss of hearing, consult a doctor immediately. Effect on driving vehicles and machinery Given the possibility of developing side effects from the central nervous system, caution should be exercised when driving vehicles and other technical devices that require increased concentration and speed of psychomotor reactions.

Compound

• ginkgo biloba extract 13 mg, glycine 147 mg, Baikal skullcap extract 5 mg; Auxiliary ingredients: MCC, calcium stearate Ginkgo biloba dry extract 120 mg (including flavonol glycosides) 26.4 mg Glycine 40 mg dry extract of Ginkgo biloba leaves 40 mg dry extract of Ginkgo biloba leaves 80 mg Ginkgo biloba leaf extract, hawthorn fruit extract MCC (anti-caking agent) calcium stearate (anti-caking agent)

Ginkgo Biloba indications for use

• The complex effect of the components on the body contributes to: improvement of blood supply to the brain, retina, myocardium (at the microcirculatory level), anti-atherosclerotic effect, reduction of platelet aggregation and prevention of thrombus formation, normal regeneration of vascular cells, improvement of mental and physical performance, reduction of meteosensitivity and improvement of the condition during periods magnetic storms, improvement of hematopoiesis and immunomodulation processes.

Ginkgo Biloba contraindications

• Reduced blood clotting, erosive gastritis, gastric and duodenal ulcers in the acute phase, acute cerebrovascular accidents, acute myocardial infarction, arterial hypotension, pregnancy, lactation, children and adolescents under 18 years of age, hypersensitivity to ginkgo biloba preparations.

Ginkgo Biloba dosage

• 0.2 g 0.45 g 0.5 g 370 mg 40 mg 80 mg

Ginkgo Biloba side effects

• Ginkgo Biloba C is well tolerated and side effects are rare. From the digestive system: dyspeptic disorders, nausea, heartburn (usually mild, temporary). From the central nervous system: headache, dizziness. Allergic reactions: skin rash, itching. Other: decreased blood clotting (after long-term use).

Drug interactions

The use of the drug is not recommended for patients constantly taking acetylsalicylic acid, anticoagulants (direct and indirect action), as well as drugs that reduce blood clotting. Isolated cases of bleeding are possible in patients simultaneously taking anticoagulants; The causal relationship of these bleedings with the use of Ginkgo biloba preparations has not been confirmed. When used with antihypertensive drugs, the antihypertensive effect may be potentiated.

Overdose

Cases of drug overdose have not been reported to date. Ginkgo Biloba is well tolerated.

Storage conditions

• store in a dry place
• keep away from children
• store in a place protected from light

Information provided

Photo of the drug

The description is valid on 25.02.2015

• Latin name: Ginkgo Folium
• ATX code: N06DX02
• Active substance: Ginkgo Biloba leaf extract (Ginkgo Bilobae foliorum extract)
• Manufacturer: ZAO Evalar (Russia), Queisser Pharma GmbH and Co. KG" (Germany)

Compound

Compound Ginkgo Biloba Evalar:

• dry extract of Ginkgo Biloba leaves;
• Glycine.

1 tablet Ginkgo Biloba Doppelgerz contains:

• dry leaf extract – 30 mg;
• vitamin B1 – 1.4 mg;
• vitamin B2 – 1.6 mg;
• vitamin B6 – 2.0 mg.

Compound Ginkgo Biloba Forte:

• Ginkgo Biloba extract;
• green tea;
• pollen;
• dried onions;
• lactose monohydrate;
• stearic acid;
• calcium stearate;

Composition of powder in 1 capsule Ginkgo Mind:

• standardized extract of dry Ginkgo biloba – 0.04 g;
• microcrystalline cellulose (MCC) – 0.109 g;
• calcium stearate – 0.001 g.

Release form

Preparations based on Ginkgo Biloba are presented, as a rule, in the form of tablets from leading pharmaceutical companies with various auxiliary components and biological additives:

• Tablets from Doppelhertz, for example, in addition to the main active component, they contain B vitamins.
• Evalar supplies capsules or tablets of 40 pieces in dark plastic bottles. The pack contains 1 bottle with the oral form of the drug.
• Ginkgo Biloba Forte– capsules weighing 0.42 g in cell blisters of 10 pieces. A cardboard pack contains 4 contour plates.
• Ginkgo Mind- hard gelatin capsules of brown color (various shades from light brown to dark are allowed), which contain a powder from yellow to light brown in color with white and dark inclusions. The cardboard packaging contains 2 contour cell blisters of 15 pieces each (a total of 30 capsules per box).
• Tincture Prepared independently from dry leaves of the Ginkgo Biloba or Ginkgo biloba tree.

pharmachologic effect

Wikipedia defines the Ginkgo tree as a gymnosperm relict plant, like spruce and pine, which is often called a living fossil. Roasted seeds and boiled leaves as tea have long been used as food in the areas where it grows and in Chinese folk medicine. At the end of the twentieth century, the Ginkgo Biloba tree began to be actively used in traditional pharmacy due to its biologically active substances ( bioflavonoids , terpene trilactones , alkaloids, organic acids, proanthocyanidins, flavonoids) isolated from its leaves. In addition, the plant contains a large number of micro- and macroelements.

The medicinal properties of Ginkgo-based drugs are varied, however, most often drugs are used due to vasoactive pharmacological effects . The constituent components are capable of inhibiting the activity of the phosphodiesterase enzyme, as a result of which cyclic acid accumulates in smooth muscle cells. guanosine monophosphate (cGMP) , and the concentration of calcium ions in the cytoplasm decreases. This manifests itself in relaxation of the muscular wall of blood vessels and a decrease in its tone. In addition, the effect of the leaf extract extends to the endothelium, enhancing the synthesis of a relaxing factor, which provides significant improved blood flow , including renal and cerebral.

The biological components of a pharmaceutical drug also affect the blood system, changing its rheological properties, preventing the development of thrombosis , reducing the adhesive properties of red blood cells and platelets, reducing the release of mediators that help increase vascular tone in the arterial bed. The mechanism of antiplatelet action is to inhibit the activity of PAF (platelet activating factor).

Ginkgo Biloba has a strong antioxidant effect , which is realized through various biochemical interactions. First of all, in this vein it is worth noting flavonoid glycosides . Possessing P-vitamin activity, they are able to bind to ions copper, iron, manganese and other metals, forming complex compounds and reducing the concentration of free radicals. In addition, they prevent biological destruction and... The extract also contains terpenoids, copper, selenium, potassium and phosphorus , implementing other mechanisms of antioxidant effect.

Anti-ischemic properties bilobalida , one of the active components of Ginkgo leaf extract, determines the use of a pharmaceutical drug in cardiology and treatment vascular insufficiency . This ability of the active substance is especially well realized under hypoxic conditions, since due to an increase in mitochondrial expression and an increase in the level of mRNA, the activity of cytochrome C oxidase is maintained, which is manifested in an increase in the respiratory activity of mitochondria.

The plant can be used in neurology, because the drug has neuroprotective properties , reducing the risk of spontaneous and oxidative apoptosis by reducing the activation of NMDA receptors and their effect on calcium-dependent mechanisms of programmed cell death. In addition to the targeted effect on the nerves, the drug helps to normalize carbohydrate metabolism, affects the metabolic properties of norepinephrine, and, due to which, it is realized antidepressant And nootropic effects therapeutic agent.

The use of Ginkgo Biloba extract is also advisable in nephrology, since the constituent components have protective properties against kidney tissue. Nephroprotective effect is realized through a decrease in lipid peroxidation, which protects cellular structures from damage. The drug also reduces the severity of some other tubular disorders. Do not forget that the plant also has diuretic properties , since renal blood flow improves significantly and the glomerular filtration rate increases.

Pharmacodynamics and pharmacokinetics

The pharmacokinetic abilities of drugs based on the active components of Ginkgo Biloba extract have not been sufficiently studied at the moment.

Indications for use of Ginkgo Biloba

• unjustified feeling of fear;
• discirculatory ;
• cerebral and myocardial vessels;
• disruption of the physiological rhythm of sleep and wakefulness;
• arteriopathy of the lower extremities ;
• general malaise;
• dementia in the background ;
• cerebrovascular disorders;
• as an additional source polyphenols And flavonoids when they are insufficient.

Indications for use can be significantly expanded through the use of pharmaceutical preparations based on Ginkgo Biloba in geriatrics . It is prescribed for age-related macular degeneration and hypoacusis , disorders of mental activity, neurosensory disorders , including tinnitus, to improve memory and learning ability.

Contraindications for Ginkgo Biloba

Absolute contraindications to the use of a homeostatic remedy:

• increased individual sensitivity to the constituent components of a pharmaceutical product;
• acute cerebrovascular accidents;
• in the acute phase;
• decreased blood clotting;
• arterial hypotension ;
• spicy ;
• pregnancy and breastfeeding;
• age category under 16 years.

Pathological conditions when Ginkgo-based preparations can be used carefully , subject to constant medical supervision:

• – increases the risk of developing seizures;
• – the possibility of complications of the pathological process;
• planned surgical interventions or postoperative regimen - the risk of developing profuse bleeding increases;
• in the presence of risk factors for development intracranial hemorrhage .

Side effects

Typically, medicines based on Ginkgo Biloba are well tolerated by patients, since the plant nature of the pharmaceutical preparation is much closer to the natural, physiological diet than artificially synthesized components. In some cases, the following side effects may occur:

• digestive disorders;

Ginkgo Biloba, instructions for use (Method and dosage)

Instructions for Ginkgo Biloba Evalar

The tablets are taken orally. It is recommended to swallow the capsule whole, without crushing or chewing, but with a sufficient amount of water. The pharmaceutical drug is used during meals, since the gastrointestinal tract is maximally tuned to absorption and the effectiveness of the therapeutic agent in this case increases. The starting dosage is 1-2 capsules 1-2 times a day. The duration of the course of conservative treatment is selected individually; as a rule, the duration is at least 3 months. Repeated therapy can be prescribed only after 2-3 months.

How to take Ginkgo mind

Ginkgo um is available in pharmacies in the form of capsules for oral use. Capsules are taken regardless of food intake in uncrushed form. It is also not recommended to chew them; you should just drink them with enough water. For symptomatic treatment cerebrovascular accidents, the frequency of administration is 3 times a day, and the dosage is 1-2 capsules (40 or 80 mg, respectively, when converted to a dry standardized extract). The course of such therapy lasts at least 8 weeks.

If a pharmaceutical drug is used for correction of peripheral circulation , then the scheme and dosages change somewhat. It is prescribed to take 1 capsule three times a day or 2 tablets twice a day, depending on individual indications and the body’s response to the drug. The therapeutic course lasts at least 6 weeks. Conservative rehabilitation vascular and involutional diseases of the inner ear follows an identical pattern.

Use of leaves: preparation of Ginkgo tincture

Pour the leaves of the plant with 40% alcohol or vodka in a ratio of 1:10. Let it brew in a dark place (limiting exposure to natural and artificial light is a necessary condition for the correct preparation of the medicinal solution) for 2 weeks, periodically shaking and straining, after which the tincture will be ready and all that remains is to find out how to take the medicine.

The standard dosage is 10 to 15 drops diluted in half a glass of water 2 times a day, immediately before meals. The amount of therapeutic concentrate is determined based on the patient’s weight. The conservative course lasts 1 month. It is recommended to take 3 courses every year, since with prolonged use of Ginkgo its therapeutic properties only become stronger.

Application of the herb

Before preparing a medicinal solution and using Ginkgo herb, it should be crushed. Next, pour 1 tablespoon of the plant mixture into 1 glass of boiling water and cook in a water bath for 15 minutes, then leave to steep for half an hour. To obtain a beneficial pharmaceutical effect, take 1/3 glass 3 times a day before meals. The duration of the course is 1 month. Repeated treatment can be carried out with a break of 2 weeks.

Overdose

The medical literature does not describe cases of overdose of any form of the drug.

Interaction

Pharmaceutical preparations based on Ginkgo Biloba should not be used in combination therapy with drugs that have anticoagulant or antiplatelet activity , And non-steroidal anti-inflammatory drugs due to an increased risk of bleeding.

Terms of sale

The medicine is available for free sale at pharmacy kiosks and other unlicensed points of sale.

Storage conditions

Preparations with Ginkgo Biloba should be stored in a dry place, protected from light and out of the reach of children. The temperature should not exceed 25 degrees Celsius.

Best before date

special instructions

Growing at home

Various sources describe successful attempts to independently grow the Ginkgo plant, which is the main component of the pharmaceutical drug. However, before you begin this difficult task, you should definitely familiarize yourself with the sequence of actions in order to realize at home the entire range of beneficial therapeutic effects of the plant and all its parts. It should also be noted that self-grown tree has some advantages , for example, a special pattern of leaves, which makes Ginkgo look like ancient ferns.

Planting and caring for a tree is not burdensome, because the plant is not demanding. A prerequisite for keeping Ginkgo is cool wintering in a temperature range from 0 to 6 degrees. Growing in the Moscow region or in another similar climate requires placing the plant in the refrigerator on a separate shelf. Also in winter you should limit water regime , however, it is also impossible to overdry the soil. Otherwise, if the required temperature and water balance are not maintained, the life cycles of Ginkgo will become confused, which will inevitably lead to the death of the plant.

Benefits and harms of Ginkgo Biloba

First of all, of course, it should be noted that all those positive aspects use of the pharmaceutical drug due to which it is prescribed. The following are considered particularly important:

• improvement of systemic blood flow at the main and microcirculatory levels;
• antioxidant effect;
• change in the rheological properties of blood towards antiplatelet properties;
• anti-ischemic effect;
• nephro- and neuroprotective effects.

Typically, the pharmaceutical drug is well tolerated by patients who use it in conservative therapy, however with increased individual sensitivity Certain side effects may be observed, interpreted as an adverse effect of the constituent components. Indigestion, drug allergies, headaches - all this is described in reviews of Ginkgo by individual users, which indicates a very poor prevalence of side effects of the active components of the herbal preparation.

Of course, both benefits and harm can be observed from the use of a drug, but the positive aspects of using a pharmaceutical drug are much broader than the negative ones and have proven scientific validity, which is why Ginkgo Biloba has gained such a good reputation among qualified specialists in the field of homeopathic remedies.

Analogs

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Analogues of Ginkgo Biloba represent a group of pharmaceutical preparations based on this plant, but with different trade names, dosage of the active component and other minor features. The most popular analogue is considered Ginkgoum – 40 mg capsules, the active ingredient of which is leaf extract Ginkgo biloba . The drug, like preparations based on Ginkgo Biloba, has a wide range of pharmaceutical properties, but the main focus of its use is angioprotective action to maintain the normal functioning of cardiovascular and brain activity.

That is, Ginkgo biloba exhibits its therapeutic capabilities to a greater extent in relation to rheological parameters of blood and vasomotor response of large vessels , which allows for more selective treatment. Therefore, Ginkgo mind is usually prescribed for the correction of peripheral and cerebral circulation, in contrast to Ginkgo Biloba, the range of indications of which covers a large number of different nosological units.

Ginkgo Gotu Kola – another popular analogue of drugs based on Ginkgo Biloba. Its peculiarity is the presence of a second active ingredient. Gotu Kola is a medicinal plant that belongs to the parsley family and has long been used in medicine. Thanks to this combination of natural components, the indications for the use of a pharmaceutical drug in the form of tablets are complemented by various traumatic lesions of the skin , since Gotu Kola contains biological components necessary for the formation of collagen structures.

The pharmaceutical properties of the drug based on two plant extracts allow not only to fight rough scars and after burns, cuts or other types of injuries, but also to promote rapid healing of trophic ulcers , which otherwise epithelialize over a long period of time. However, such additional capabilities of the drug to some extent increase the price, which is not accepted unconditionally by all categories of patients.

During pregnancy and lactation

During pregnancy and breastfeeding, the drug should be taken strictly as prescribed by the doctor.

Reviews of Ginkgo Biloba

Pharmaceutical preparations based on the Ginkgo tree are very popular, because they are a kind of panacea in the treatment of a large number of nosological entities. The therapeutic properties of the medicinal plant have been known since ancient times, which creates a special credibility for such a conservative treatment, combining folk remedies and the achievements of modern pharmacy.

Reviews of Ginkgo Biloba Evalar should be noted separately, because this is the most common drug based on this plant. A huge number of forums and thematic sites are full of recommendations for its use, especially since it does not require the knowledge and skills of a medical professional or gardener, because many grow Ginkgo on their own, which consumes a lot of effort and time.

Another positive aspect of the tablets is the gradual onset of pharmaceutical effects - such a temporary duration of therapy allows you to fully adapt and adjust all the necessary systems and metabolic chains, which affects the final favorable result.

Reviews from doctors about Ginkgo Biloba are extremely mixed, as are the case with most medicines whose active ingredient is a herbal component. Of course, some medical specialists approve of the use of such conservative sanitation, since they have independently observed the positive dynamics of pathological conditions in the patients under their supervision.

However, a considerable proportion of qualified medical workers remain deaf to such not entirely traditional means of treating nosological entities. Of course, their argument is based on little knowledge of Ginkgo-based pharmaceuticals and the short duration of their use, which in practical terms does not provide reliable conclusions about long-term side effects or adverse consequences of drug therapy. They are also unable to refute the described cases of cure with Ginkgo Biloba, which once again indicates the clinical effectiveness of the mechanisms of action of the drug that have not yet been fully studied.

Ginkgo Biloba price, where to buy

The price of Ginkgo Biloba largely depends on the form of purchase of the pharmaceutical preparation or preparations for self-cultivation of the plant and the country where they are directly purchased. For example, the price of Ginkgo Biloba in the USA is approximately $23.

On the territory of the Russian Federation, pharmaceutical preparations based on Ginkgo are also not considered expensive drugs; you can buy Ginkgo Biloba in Moscow for 150 rubles. As for the situation with self-growing at home, a young tree can be purchased for 250 rubles, and a seedling for 200 rubles. Even leaves are sold separately, which can be used to make tea or tinctures.

• Online pharmacies in Russia Russia
• Online pharmacies in Ukraine Ukraine
• Online pharmacies in Kazakhstan Kazakhstan

Description of Ginkgo biloba

It is a unique relict species, the only one preserved over many millions of years of the planet’s development. It belongs to the primitive gymnosperms of the dioecious type. The reproductive cells of a plant are divided into female and male. Male trees produce pollen, and female trees produce seed buds. They are pollinated by air currents. This deciduous tree has shiny, smooth grayish-brown bark. He can live up to two thousand years.

The presented trees have branches without leaves, on which there are dwarf growths with interesting bunches of fan-shaped long-petioled leaves of a bluish-green color. These sinewy, leathery leaves exhibit varying degrees of segmentation and lobulation. Their reproductive structures include female primordia and male microsporangia. The male cluster-shaped flowers are yellow-green and have numerous stamens.

While the female flowers are located on very long stalks with unusual branching at the ends. They always end with a seed germ. The powerful Ginkgo biloba often blooms in May. Immediately after pollination and subsequent fertilization, small ovules turn into plum-shaped yellow fruits. They consist of large dihedral kernels resembling nuts and are covered with pulp. Reproduction of this plant is carried out vegetatively and with the help of seeds.

Such unusual trees can be found in Japan and France, and the species is also cultivated in South Korea.

Useful properties of Ginkgo biloba

Today, only the leaves of the plant are used for medicinal purposes. They are harvested in the fall during the growing season. Linalool esters and phenylpropane derivatives were found in the leaves, as well as in the seeds and wood. The composition contains special sesquiterpenes and tricyclic diterpenes. Ginkgo biloba roots contain a unique ginkgolide. The content of ginkgolides varies significantly in different preparations.

Thanks to exceptional specific substances, the plant tends to dilate blood vessels, easily increasing the elasticity of the vessel walls. In addition, Ginkgo biloba perfectly fights all sorts of different inflammatory processes, since it is possible to inhibit the activation factor. Due to this factor, drugs are indicated for myocardial infarction, bronchial asthma, etc.

An important component is the essential flavin glycosides, which have surprisingly powerful antioxidant properties. The strong therapeutic effect exerted by the plant on the human body includes a decrease in blood levels, a decrease in edema, increased strength of the walls of blood vessels and the normalization of metabolic processes.

It has also been proven to be useful for preventing lipid peroxidation and normalizing blood pressure. It should be mentioned that numerous drugs can have a beneficial effect on human thinking and memory, improving the speed of processes in the brain. To restore blood circulation processes, Ginkgo biloba is used very often by many modern doctors.

Uses of Ginkgo biloba

Due to the fact that the antioxidant and angioprotective properties of the plant have been proven, its leaves have become widely used in medicine. Various pharmaceutical drugs are primarily indicated for various manifestations of cerebral atherosclerosis. Ginkgo biloba also has a positive effect on the aging body, including behavioral and psycho-emotional disorders. They are usually accompanied by obstruction of cerebral vessels.

It is worth noting the benefits of the drugs for serious visual and hearing disorders. Regular use of the prescribed drug for a long time helps not only improve memory and excellent concentration, but also eliminates dizziness and. Ginkgo biloba is effective for intellectual activity, venous disease and obliterating arteriosclerosis, as it improves the rheological properties of blood and reduces thrombus formation.

Additional advantages in the treatment of diseases include anti-inflammatory effects and vasoregulatory effects on the human body. Often, drugs are prescribed for dangerous systemic diseases accompanied by serious circulatory disorders. These include, in particular, and.

Ginkgo biloba leaves

The long-petioled leaves of Ginkgo biloba contain large quantities of flavonoids, procyanidins, diterpenoids, as well as bilobalide and ginkgolides. One of the presented alkaloids is a fairly powerful antioxidant that binds all substances that provoke vasoconstriction and the inevitable appearance of blood clots.

Tincture of Ginkgo biloba leaves. This product is a unique pharmaceutical preparation, which is characterized by many beneficial properties. The range of its therapeutic effects is wide, it is due to its amazing effect on all metabolic processes occurring in the cells of any human body. When using this drug, you can dilate blood vessels, restore neuron metabolism, significantly reduce cholesterol levels and normalize arterial blood pressure.

This drug is often prescribed for serious diseases of the cardiovascular system, for the treatment of cerebral vascular insufficiency, for multiple sclerosis and intermittent claudication syndrome, as well as for complaints of tinnitus. It is also indicated for diabetes and hemorrhoids. Together with the main therapy, Ginkgo biloba has a positive effect on the treatment of migraines, deafness, bronchial asthma, impotence and toxic shock.

It has been proven that it can prevent the development of extremely dangerous conditions such as heart attack and stroke. Ginkgo biloba tincture can be used by any age group. After just a week of regular use, you will be able to observe positive dynamics. This powerful stimulant of attention, memory and mental potential amazes with its effect on the human body.

To prepare the product at home, you need to take vodka and pour the leaves of the plant at the rate of 1 part leaves to 10 parts vodka. After infusing for two weeks in a very dark place, the Ginkgo biloba tincture should be carefully strained. You can take the medicine 10-15 drops diluted in 100 grams of water. In this case, the course of treatment should not be less than one month. Modern experts advise conducting three full courses per year. This treatment regimen gives positive results that last for a long time.

This tincture can also be used as an excellent external remedy for facial rejuvenation.

Ginkgo biloba extract

Ginkgo biloba tree extract has long been used by ancient Chinese healers. It improves not only memory and thinking, but also has a beneficial effect on a person’s overall well-being. Today, this drug is part of many pharmaceuticals that are used for effective prevention and effective treatment of a wide variety of diseases.

The extract from the presented plant is indispensable for disorders of the blood supply to the brain. The steroids in the extract are directly involved in important cell growth processes, exerting a beneficial effect on the overexpression of the PBR type. The drug is indicated for the destruction of life-threatening cancer cells, and is also used for preventive purposes in the treatment of complex forms of various malignant neoplasms.

Modern doctors have proven the benefits of Ginkgo biloba extract for diseases of the lungs and heart, and for bronchial asthma, due to its unique antispastic properties. It is often prescribed as an anthelmintic and can be used externally. In the very early stages of Alzheimer's disease, the drug significantly slows down the decline of all mental abilities. In addition, it has a vasodilating effect, increases vascular elasticity and has an antihypoxic effect.

How to take ginkgo biloba? For use, it is recommended to dilute the drug in water and strictly follow the prescribed dosage. As a rule, the dose does not exceed 20 drops. The course of treatment is from 30 to 40 days. If necessary, treatment can be repeated after 3-4 months.

Ginkgo biloba seeds

The ellipsoidal seeds are no more than 3 cm long. They have a rather fleshy outer shell. Using seeds, you can easily propagate Ginkgo biloba. Before sowing, they must be thoroughly cleared of the fleshy pericarp, and then sown to a depth of about 5 cm. As a rule, germination time can be about 30 days. Since the plant is considered fast-growing, in the first year of its life all seedlings will grow by 15 cm. They quickly form shoots and produce active shoots, starting from the stump to the very root.

It should be mentioned that seedlings do not tolerate transplantation very well. After this procedure, they will not grow for a very long time.

Ginkgo biloba tea

Delicious Ginkgo biloba tea is renowned for its incomparable medicinal value. It can also be included in special drinks along with honeysuckle. The combination of roots and leaves of the plant significantly enhances the healing effect of tea. After a 30-day course of treatment, you will be able to notice a unique increase in your immunity. In addition to a general improvement in well-being, mental reactions will become sharper and memory will become more flexible.

Ginkgo biloba tea promotes improvement in all organs and systems, it restores blood circulation in all blood vessels, increases flow to the brain, and also protects cells from numerous free radicals. It delays the aging of the body, preventing strokes and heart attacks. Elderly patients experience slow platelet activation.

It is enough to replace your regular morning tea with this drink to replenish your vitality and well-being.

Ginkgo biloba for children

Various drugs based on this plant are not prescribed to children under 16 years of age, since there is no reliable information on the safety and effectiveness of the use of these drugs.

Ginkgo biloba oil

Incomparable oil based on Ginkgo biloba is considered an incredibly powerful restorative agent. When used externally, it has a beneficial effect on split ends and weakened hair. The oil perfectly strengthens the hair roots, restoring the scalp. By enhancing the functionality of the follicles, your hair will become shiny and thick. This cosmetic product has also long been used in everyday skin care. It can cure eczema, ulcers and other serious skin diseases.

Contraindications for Ginkgo biloba

The main contraindication for the use of various preparations containing Ginkgo biloba is the period of pregnancy and lactation. In case of excessive sensitivity to active substances, treatment should be stopped immediately.

Expert editor: Sokolova Nina Vladimirovna| Herbalist

Education: Diploma in General Medicine and Therapy received from the University named after N. I. Pirogov (2005 and 2006). Advanced training at the Department of Herbal Medicine at the Moscow People's Friendship University (2008).